Results 231 to 240 of about 190,753 (310)

Phage homing endonuclease amplifies anti-defense genes to evade bacterial immunity. [PDF]

Nat Commun
Chihara K, Azam AH, Egorov AA, Terenin I, Hashino M, Watashi K, Horiba K, Hauryliuk V, Kiga K.   +8 more
europepmc   +1 more source

Clostridioides difficile‐Derived Extracellular Vesicles Induce Proinflammatory Responses in Macrophages

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Clostridioides difficile (CD) is a leading cause of antibiotic‐associated diarrhoea in both hospitalized and non‐hospitalized patients. This study explores the role of extracellular vesicles (EVs) derived from Clostridioides difficile strain 630 (CD630‐EVs), which released spherical EVs during in vitro culture, in modulating pro‐inflammatory ...
Fangfang Fan, Yu Zeng, Qianli Zhao, Tongxuan Su, Yining Shen, Wei Chen, Cen Jiang, Qi Ni, Yiyue Liu, Ru Fan, Danfeng Dong, Yibing Peng   +11 more
wiley   +1 more source

Comparative morphological, genomic, and functional characterization of two newly isolated lytic caudoviricetes phages targeting Escherichia coli and Salmonella. [PDF]

Sci Rep
Shaaban MT, Sallam O, Manikandan SK, Ahmed AAM, Osaili TM, Hamad M, El-Keblawy A.   +6 more
europepmc   +1 more source

Generation of Nano‐Antibodies Targeting the SNMP1 Membrane Receptor of Spodoptera littoralis Using Extracellular Vesicles

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
Extracellular vesicles (EVs) represent an excellent platform for the expression of recombinant membrane proteins and their use in llama immunization to generate nano‐antibodies (Nabs). In this study, we present a novel strategy, termed the multi‐layer approach, for EV immobilization in biopanning and ELISA applications.
Alexis Dogliani, Laura Fradale, Céline Valeille, Christian Cambillau, Emmanuelle Jacquin‐Joly, Alain Roussel, Josiane Kassis‐Sahyoun   +6 more
wiley   +1 more source

Genomic and biological characterization of lytic phages infecting Pseudomonas syringae associated with almond bacterial blast. [PDF]

Sci Rep
Hoang CV, Fan J, Lee H, Bhasin L, Nguyen D, Duran A, Quaal R, Ganiger S, Santiago L, Adaskaveg JE, Maguvu TE, Trouillas FP, Olawole OI.   +12 more
europepmc   +1 more source

Isolation of Extracellular Vesicles From Gram‐Negative Bacteria: A Solid Medium‐Based Method Analysis

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) produced by gram‐negative bacteria have gained increased scientific interest over the last years due to a growing understanding of their roles in pathogenesis and biotechnological potential. However, isolating such nanoparticles is technically challenging. Here, we evaluated a rapid and reproducible protocol for EV
Roberto G. M. Guardatti, Jhonatha R. Cordeiro‐Moura, Jhon J. Artunduaga Bonilla, Stefanie C. da Costa, Anderson S. Cabral, Bruna Montalvão, Flávia G. C. Reis, Leonardo Nimrichter, Márcio L. Rodrigues, Juliana Rizzo, Renata C. Picão   +10 more
wiley   +1 more source

Isolation and Genome Annotation of TicTac, an EK1 Cluster Bacteriophage with Podovirus Morphology. [PDF]

MicroPubl Biol
Allgood M, Githuku E, Bonson R, Edwin I, Granander A, Kopp N, Kunyu M, Mathews A, Ngandu P, Pepin A, Serve KC, Widman K, Zelenka E, Zuck C, Grinath AS, Harris T, Shurley J, Thomas M.   +17 more
europepmc   +1 more source

Comparative Proteomic Profiling of Clinical Klebsiella pneumoniae Strains and the Corresponding Outer Membrane Vesicles

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Klebsiella pneumoniae (K. pneumoniae) has become a global threat due to the convergence of carbapenem resistance and hypervirulence. Outer membrane vesicles (OMVs) play important roles in bacterial pathogenicity, yet their functional coordination with strains remains unclear.
Zongping Li, Jingyuan Xi, Xinmiao Jia, Yangzhige He, Guibin Wang, Shiyu Chen, Xiaobing Chu, Qian Zhang, Ying Zhu, Wei Yu, Peiyao Jia, Xiaoyu Liu, Qiwen Yang   +12 more
wiley   +1 more source

Genome Sequences of <i>Streptomyces griseus</i> Phages Destructrice and Rikishi. [PDF]

MicroPubl Biol
Powell EA, Wortman AO, Tyler KE, Alfonso-Perez K, Bez GA, Buechlein CR, Day MD, Diab TT, Henderson IG, Ishola TE, Rider RS, Seiler DN, Stooksberry CS, Wary AE, Merkle JA.   +14 more
europepmc   +1 more source

Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics

JGH Open, Volume 10, Issue 4, April 2026.
ABSTRACT Crohn's disease (CD) is a chronic inflammatory condition of the bowel with a rising global incidence. Its complex etiology involves genetic susceptibility, environmental factors, and alterations in the gut microbiota, leading to dysregulated immune responses.
Yoon‐Kyo An, Robert Gilmore, Graham Radford‐Smith, Jakob Begun   +3 more
wiley   +1 more source