Results 231 to 240 of about 1,053,752 (301)
ABSTRACT Background Colorectal liver metastasis (CRLM) is a leading cause of mortality in colorectal cancer (CRC), yet current surveillance often misses occult micrometastases, underscoring an urgent need for early non‐invasive biomarkers and mechanistic insights.
Yuejin Sheng +4 more
wiley +1 more source
Genome‐Wide Analysis of Protein Binding to DNA in Plastids by ptChIP‐seq
Abstract Plastids contain their own genomes encoding essential components of the photosynthetic apparatus and gene expression machinery. Transcription in plastids is mediated by two RNA polymerases, nuclear‐encoded (NEP) and plastid‐encoded RNA polymerase (PEP).
V. Miguel Palomar +3 more
wiley +1 more source
Alcohol‐Associated Liver Disease: Epidemiology, Pathogenesis, and Emerging Therapeutic Targets
ALD imposes a growing global burden influenced by alcohol consumption, genetic susceptibility, and obesity. Its pathogenesis involves interactions among ethanol metabolism, oxidative stress, innate immune activation, regulated cell death, and disruption of the gut–liver axis.
Shuyan Wang, Yirui Hu, Huikuan Chu
wiley +1 more source
Characterization and genomic analysis of a jumbo Aeromonas hydrophila phage BMBAH1, representing a candidate novel viral genus. [PDF]
Huo S +5 more
europepmc +1 more source
Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies
Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo +8 more
wiley +1 more source
Artificial Intelligence–Driven Graph Methods for Microbiome Research: A Systematic Review
Multi‐omics and microbiome‐derived datasets were converted into deterministic and probabilistic network representations for downstream classical graph analysis and graph representation learning. This framework enables link prediction, relationship discovery, and node clustering to improve interpretation of complex biological interactions.
Cedrique Shum‐Tim +9 more
wiley +1 more source
The broad ecological range of Salmonella enterica serotype Typhimurium is associated with dynamic gain and loss of accessory genes, including plasmid‐associated antimicrobial resistance (AMR) genes, along with positive selection on core genes, potentially contributing to its differential adaptation across food animal and non‐food animal reservoirs ...
Leela Ohri +8 more
wiley +1 more source
A Bacillus Phage From Bangladeshi Soil, Phage APU1: Genomic Characterisation and Comparative Genomic Analysis. [PDF]
Haider A +10 more
europepmc +1 more source
ABSTRACT Salmonella remains one of the most important foodborne pathogens associated with poultry products, despite substantial progress in processing hygiene and antimicrobial interventions. This review critically examines the sources, transmission routes, and control strategies for Salmonella in vertically integrated broiler production systems ...
Deepak Subedi +6 more
wiley +1 more source
ABSTRACT Salmonella enterica remains a major foodborne pathogen in poultry‐processing environments, where its persistence is largely attributed to biofilm formation on food‐contact and non‐food‐contact surfaces. Despite extensive research on Salmonella control, persistent contamination continues to challenge food safety due to the complex interplay ...
Md Anamul Hasan Chowdhury +4 more
wiley +1 more source

