Results 261 to 270 of about 191,093 (287)
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Phage Comparative Genomics Lab Manual

2021
A lab manual containing detailed instructions for several bioinformatics tools (dot plots, Phamerator maps, phylogenetic trees, and gene content similarity), all of which enable students to perform comparative genomic analyses on phages.
Kapinos, Andrew   +2 more
openaire   +1 more source

Genomics: From Phage to Human

2003
The first genome, that of RNA bacteriophage MS2, was sequenced in 1976, in a truly heroic feat of direct determination of an RNA sequence [225]. This was followed by the genome of bacteriophage ϕX174, the first triumph of the new, rapid sequencing methods developed in the laboratories of Walter Gilbert and Fred Sanger [553,743].
Eugene V. Koonin, Michael Y. Galperin
openaire   +1 more source

Evolution of Tailed Phages: Insights from Comparative Phage Genomics

2005
Abstract Many phage researchers believe that phages are as old as their bacterial hosts. If this hypothesis is true, then we have to postulate elements of vertical evolution for phages. In view of the postulated antiquity of these relationships we might not expect sequence similarities between more distantly related phages.
Harald Brüssow, Frank Desiere
openaire   +1 more source

Phage Sometimes Remodel Host Genomes

Microbe Magazine, 2007
When cyanophage infect Prochlorococcus, they kill some host bacteria but remodel others in ways that makes the survivors hardier, according to Sallie Chisholm of Massachusetts Institute of Technology (MIT) in Cambridge, Mass., Debbie Lindell of the Technion Israel Institute of Technology (TIIT) in Technion City, Haifa, Israel, and their collaborators ...
openaire   +1 more source

Phage Integrases for Genome Editing

2016
Phage integrases are prokaryotic site-specific recombinases that perform precise cut-and-paste recombination between their short attB and attP recognition sequences. These enzymes work in cellular environments ranging from bacteria to mammalian cells and have become useful genome engineering tools.
openaire   +1 more source

Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors

Cell, 2022
Basem Al-Shayeb   +2 more
exaly  

Phage genome engineering with retrons

Nature Biotechnology
Ilya Osterman, Rotem Sorek
openaire   +2 more sources

Guiding phage therapy with genomic surveillance

Nature Microbiology
Leitner, Lorenz, McCallin, Shawna
openaire   +2 more sources

Popping the cork: mechanisms of phage genome ejection

Nature Reviews Microbiology, 2013
Ian J Molineux, Debabrata Panja
exaly  

Gene transfer agents: phage-like elements of genetic exchange

Nature Reviews Microbiology, 2012
Andrew S Lang, Olga Zhaxybayeva
exaly  

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