Results 171 to 180 of about 4,525,509 (335)

Phage therapy: the Escherichia coli experience

, 2005
Harald Brüssow
openalex   +1 more source

Chameleonic Nature of Aβ: Implications for Alzheimer's and Other Amyloid Diseases

BioEssays, EarlyView.
The energy landscape of Aβ reveals its flexible, “chameleon‐like” behavior, enabling diverse structures from disordered to β‐rich forms. This polymorphism facilitates aggregation, contributing to Alzheimer's disease progression, while the flat landscape also allows disaggregation, potentially slowing disease progression compared to prion proteins with ...
Birgit Strodel
wiley   +1 more source

Phages, Fitness, Virulence, and Synergy: A Novel Approach for the Therapy of Infections Caused by Pseudomonas aeruginosa [PDF]

, 2016
Charles W. Stratton
openalex   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Stability study in selected conditions and biofilm-reducing activity of phages active against drug-resistant Acinetobacter baumannii

Scientific Reports
Acinetobacter baumannii is currently a serious threat to human health, especially to people with immunodeficiency as well as patients with prolonged hospital stays and those undergoing invasive medical procedures.
Natalia Bagińska, Ilona Grygiel, Filip Orwat, Marek Adam Harhala, Adam Jędrusiak, Elżbieta Gębarowska, Sławomir Letkiewicz, Andrzej Górski, Ewa Jończyk-Matysiak   +8 more
doaj   +1 more source

Structure and genome delivery mechanism of Staphylococcus aureus phage therapy agent phi812‐K1 determined by cryo‐electron microscopy [PDF]

, 2016
Jiří Nováček, Marta Šiborová, Martin Benešík, Roman Pantůček, Jiřı́ Doškař, Pavel Plevka   +5 more
openalex   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

Coordinated gene expression within sustained STAT3‐associated chromatin conformations contributes to hepatocellular carcinoma progression

Cancer Communications, EarlyView.
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang, Sumin Yoon, Hyeokjun Yang, Nayun Choi, Su‐Hyang Han, Lark Kyun Kim, Hyoung‐Pyo Kim, Jong Hoon Park, Daeyoup Lee, Kyung Hyun Yoo   +9 more
wiley   +1 more source

Phage therapy experience at the Eliava Institute

, 2008
Mzia Kutateladze, Revaz Adamia
openalex   +1 more source

Phage therapy is highly effective against chronic lung infections withPseudomonas aeruginosa [PDF]

, 2017
Elaine M. Waters, Daniel R. Neill, Basak Kaman, Jaspreet Singh Sahota, Martha R. J. Clokie, Craig Winstanley, Aras Kadioglu   +6 more
openalex   +1 more source