Results 171 to 180 of about 116,257 (347)
A combination therapy of Phages and Antibiotics: Two is better than one [PDF]
, 2021 Xianghui Li +12 more
openalex +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Interactions of Bacteriophages with Animal and Human Organisms—Safety Issues in the Light of Phage Therapy [PDF]
, 2021 Magdalena Podlacha +6 more
openalex +1 more source
Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation
Small, EarlyView.Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt +7 more
wiley +1 more source
Small Structures, EarlyView.Cas12Fold, a deep‐learning framework tailored to Cas12 nucleases, uses evolutionary signals and iterative structure‐based alignment to resolve conformational complexity. This method outperforms general models in predicting key domains and states, accurately modeling enzymes such as Casλ.
Feng Xu +12 more
wiley +1 more source
Past and Future of Phage Therapy and Phage-Derived Proteins in Patients with Bone and Joint Infection [PDF]
, 2021 Tristan Ferry +12 more
openalex +1 more source
VIEW, EarlyView.Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan +10 more
wiley +1 more source
Microbiology and Immunology, EarlyView.ABSTRACT The extensive and indiscriminate use of antibiotics, which are intended to halt bacterial growth or eliminate them, has unintentionally given rise to antimicrobial resistance (AMR), which is a critical threat to global health. In the pursuit of alternative solutions, researchers have focused on type II toxin–antitoxin systems prevalent within ...
Hana Hasegawa +6 more
wiley +1 more source