Results 11 to 20 of about 90,396 (354)
The Epic of Phage Therapy [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2006 The present report describes the presentation given by Dr Alain Dublanchet at the Stanier/Oxford Hygiene Symposium, held in Oxford, England, on November 10, 2004. Dr Dublanchet′s lecture, entitled ‘The epic of phage therapy’, provided a sequential account of the use of phage as an antimicrobial from its discovery to its rise and fall and current ...
A. Dublanchet, Shawna Bourne
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Phage Therapy in Veterinary Medicine [PDF]
Antibiotics, 2021 To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects ...
Loponte R. +3 more
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WikiJournal of Medicine, 2021 Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war.
Joana Azeredo +6 more
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Phage Therapy: Going Temperate? [PDF]
Trends in Microbiology, 2018 Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bacterial virulence, for example, by promoting antibiotic resistance.
Rodrigo Monteiro +3 more
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Phage therapy—constraints and possibilities
Upsala Journal of Medical Sciences, 2014 The rise of antibiotic-resistant bacterial strains, causing intractable infections, has resulted in an increased interest in phage therapy. Phage therapy preceded antibiotic treatment against bacterial infections and involves the use of bacteriophages, bacterial viruses, to fight bacteria.
Anders Nilsson
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Animal Models of Phage Therapy [PDF]
Frontiers in Microbiology, 2021 Amidst the rising tide of antibiotic resistance, phage therapy holds promise as an alternative to antibiotics. Most well-designed studies on phage therapy exist in animal models. In order to progress to human clinical trials, it is important to understand what these models have accomplished and determine how to improve upon them.
Samuel Penziner +3 more
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Isolation and characterisation ofKlebsiellaphages for phage therapy [PDF]
PHAGE, 2020 AbstractKlebsiellais a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection and sepsis. Bacteriophage (phage) therapy is being considered as a primary option for the treatment of drugresistant infections of these types.
Eleanor Townsend +12 more
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Antibiotics, 2021 The emergence and evolution of antibiotic-resistant bacteria is considered a public health concern. Salmonella is one of the most common pathogens that cause high mortality and morbidity rates in humans, animals, and poultry annually.
Abdallah S. Abdelsattar +5 more
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Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2
Virology Journal, 2023 Background Bacteriophages (phages) are one of the most promising alternatives to traditional antibiotic therapies, especially against multidrug-resistant bacteria.
Mohamed S. Fayez +8 more
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Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]
, 2020 Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia +4 more
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