Results 11 to 20 of about 4,551,719 (377)
Isolation and Characterization of Klebsiella Phages for Phage Therapy [PDF]
PHAGE, 2021 Introduction: Klebsiella is a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection, and sepsis.
Eleanor Townsend +12 more
semanticscholar +6 more sources
Phage Therapy in Germany—Update 2023 [PDF]
Viruses, 2023 Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current situation (2023) of applied phage therapy and supporting research in Germany.
C. Willy +19 more
semanticscholar +5 more sources
The Epic of Phage Therapy [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2006 The present report describes the presentation given by Dr Alain Dublanchet at the Stanier/Oxford Hygiene Symposium, held in Oxford, England, on November 10, 2004. Dr Dublanchet′s lecture, entitled ‘The epic of phage therapy’, provided a sequential account of the use of phage as an antimicrobial from its discovery to its rise and fall and current ...
A. Dublanchet, Shawna Bourne
openalex +5 more sources
Phage Therapy in Veterinary Medicine [PDF]
Antibiotics, 2021 To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects ...
Loponte R. +3 more
openaire +5 more sources
Translating phage therapy into the clinic: Recent accomplishments but continuing challenges
PLoS Biology, 2023 Phage therapy is a medical form of biological control of bacterial infections, one that uses naturally occurring viruses, called bacteriophages or phages, as antibacterial agents.
Aleksandra Petrović Fabijan +4 more
semanticscholar +1 more source
WikiJournal of Medicine, 2021 Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war.
Joana Azeredo +6 more
openaire +1 more source
Animal Models of Phage Therapy [PDF]
Frontiers in Microbiology, 2021 Amidst the rising tide of antibiotic resistance, phage therapy holds promise as an alternative to antibiotics. Most well-designed studies on phage therapy exist in animal models. In order to progress to human clinical trials, it is important to understand what these models have accomplished and determine how to improve upon them.
Samuel Penziner +3 more
openaire +4 more sources
Immunogenicity of Endolysin PlyC
Antibiotics, 2022 Endolysins are bacteriolytic enzymes derived from bacteriophages. They represent an alternative to antibiotics, since they are not susceptible to conventional antimicrobial resistance mechanisms.
Marek Adam Harhala +4 more
doaj +1 more source
Phage therapy—constraints and possibilities
Upsala Journal of Medical Sciences, 2014 The rise of antibiotic-resistant bacterial strains, causing intractable infections, has resulted in an increased interest in phage therapy. Phage therapy preceded antibiotic treatment against bacterial infections and involves the use of bacteriophages, bacterial viruses, to fight bacteria.
Anders Nilsson
openalex +4 more sources
Phage Therapy: Going Temperate? [PDF]
Trends in Microbiology, 2018 Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bacterial virulence, for example, by promoting antibiotic resistance.
Rodrigo Monteiro +3 more
openalex +6 more sources