Results 11 to 20 of about 116,257 (347)

Phage Therapy

WikiJournal of Medicine, 2021
Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war.
Joana Azeredo, Jean-Paul Pirnay, Diana P. Pires, Mzia Kutateladze, Krystyna Dabrowska, Rob Lavigne, Bob Blasdel   +6 more
openaire   +2 more sources

Phage therapy

Nature Reviews Methods Primers
Bacteriophage (phages) are viruses that exclusively use bacterial cells for propagation, killing the bacterial host in the process. In phage therapy, phages are used to reduce bacterial numbers, thereby curing bacterial infections. Although this principle is conceptually straightforward, its practical application faces several hurdles.
Mikael Skurnik, Sivan Alkalay-Oren, Maarten Boon, Martha Clokie, Thomas Sicheritz-Pontén, Krystyna Dąbrowska, Graham F. Hatfull, Ronen Hazan, Matti Jalasvuori, Saija Kiljunen, Rob Lavigne, Danish J. Malik, Ran Nir-Paz, Jean-Paul Pirnay   +13 more
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The Synergistic Effect of Biosynthesized Silver Nanoparticles and Phage ZCSE2 as a Novel Approach to Combat Multidrug-Resistant Salmonella enterica

Antibiotics, 2021
The emergence and evolution of antibiotic-resistant bacteria is considered a public health concern. Salmonella is one of the most common pathogens that cause high mortality and morbidity rates in humans, animals, and poultry annually.
Abdallah S. Abdelsattar, Rana Nofal, Salsabil Makky, Anan Safwat, Amera Taha, Ayman El-Shibiny   +5 more
doaj   +1 more source

Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2

Virology Journal, 2023
Background Bacteriophages (phages) are one of the most promising alternatives to traditional antibiotic therapies, especially against multidrug-resistant bacteria.
Mohamed S. Fayez, Toka A. Hakim, Bishoy Maher Zaki, Salsabil Makky, Mohamed Abdelmoteleb, Kareem Essam, Anan Safwat, Abdallah S. Abdelsattar, Ayman El-Shibiny   +8 more
doaj   +1 more source

Characterization of the biosynthesized Syzygium aromaticum-mediated silver nanoparticles and its antibacterial and antibiofilm activity in combination with bacteriophage

Results in Chemistry, 2023
Contamination with bacteria and organic matters is becoming a serious challenge for governments and a central issue for public health. Biosynthesized silver nanoparticles (AgNPs) are currently gaining attention due to the additional properties provided ...
Salsabil Makky, Nouran Rezk, Abdallah S. Abdelsattar, Assmaa H. Hussein, Aalaa Eid, Kareem Essam, Azza G Kamel, Mohamed S. Fayez, Mohamed Azzam, Mona M. Agwa, Ayman El-Shibiny   +10 more
doaj   +1 more source

Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]

, 2020
Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia, Tavanti, Arianna, Tkhilaishvili, Tamta, Trampuz, Andrej, Wang, Lei   +4 more
core   +1 more source

The Lytic Activity of Bacteriophage ZCSE9 against Salmonella enterica and Its Synergistic Effects with Kanamycin

Viruses, 2023
Salmonella, the causative agent of several diseases in humans and animals, including salmonellosis, septicemia, typhoid fever, and fowl typhoid, poses a serious threat to global public health and food safety. Globally, reports of therapeutic failures are
Abdallah S. Abdelsattar, Mohamed Atef Eita, Zainab K. Hammouda, Shrouk Mohamed Gouda, Toka A. Hakim, Aghapy Yermans Yakoup, Anan Safwat, Ayman El-Shibiny   +7 more
doaj   +1 more source

Isolation, characterisation and experimental evolution of phage that infect the horse chestnut tree pathogen, Pseudomonas syringae pv. aesculi [PDF]

, 2020
Bleeding canker of horse chestnut trees is a bacterial disease, caused by the bacterium Pseudomonas syringae pv. aesculi, estimated to be present in ~ 50% of UK horse chestnut trees.
Jackson, Robert W., James, Sarah L., Neuman, Benjamin W., Percival, Glynn, Rabiey, Mojgan   +4 more
core   +3 more sources

The green production of eco-friendly silver with cobalt ferrite nanocomposite using Citrus limon extract

Results in Chemistry, 2023
This paper reveals a novel and greener strategy to biosynthesize Cobalt-Ferrite-Silver trimetallic nanoparticles (Co-Fe-AgNPs) using the Citrus limon extract as a bio-reducing agent. Depending on the Transmission and Scanning Electron Microscopy (TEM and
Abdallah S. Abdelsattar, Azza G. Kamel, Ayman El-Shibiny   +2 more
doaj   +1 more source

Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk

Biologics, 2021
Food safety is very important in the food industry as most pathogenic bacteria can cause food-borne diseases and negatively affect public health.
Abdallah S. Abdelsattar, Anan Safwat, Rana Nofal, Amera Elsayed, Salsabil Makky, Ayman El-Shibiny   +5 more
doaj   +1 more source