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Phage Therapy in Germany—Update 2023 [PDF]
Viruses, 2023 Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current situation (2023) of applied phage therapy and supporting research in Germany.
C. Willy +19 more
semanticscholar +5 more sources
Isolation and Characterization of Klebsiella Phages for Phage Therapy [PDF]
PHAGE, 2021 Introduction: Klebsiella is a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection, and sepsis.
Eleanor Townsend +12 more
semanticscholar +6 more sources
The Epic of Phage Therapy [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2006 The present report describes the presentation given by Dr Alain Dublanchet at the Stanier/Oxford Hygiene Symposium, held in Oxford, England, on November 10, 2004. Dr Dublanchet′s lecture, entitled ‘The epic of phage therapy’, provided a sequential account of the use of phage as an antimicrobial from its discovery to its rise and fall and current ...
A. Dublanchet, Shawna Bourne
openalex +5 more sources
Phage therapy: progress in pharmacokinetics [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2018 The concept of phage therapy exists in the history and it has been ignored for a long time, but the consequence of drug resistance in pathogen bacteria has forced the forgotten kingdom of phage therapy to be re-explored.
Masood, Ardas +2 more
core +11 more sources
Phage Therapy in the Postantibiotic Era [PDF]
Clinical Microbiology Reviews, 2019 Antibiotic resistance is arguably the biggest current threat to global health. An increasing number of infections are becoming harder or almost impossible to treat, carrying high morbidity, mortality, and financial cost.
F. G. Gordillo Altamirano, J. Barr
semanticscholar +3 more sources
Phage Therapy in Veterinary Medicine [PDF]
Antibiotics, 2021 To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects ...
Loponte R. +3 more
openaire +5 more sources
Frontiers in Pharmacology, 2023 Background: Chronic Bacterial Prostatitis (CBP) is inflammation of the prostate caused by bacterial infection. An estimated 8.2% of men have prostatitis, most commonly under the age of 50.
Apurva Virmani Johri +6 more
doaj +1 more source
Phage Therapy: Going Temperate? [PDF]
Trends in Microbiology, 2018 Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bacterial virulence, for example, by promoting antibiotic resistance.
Rodrigo Monteiro +3 more
openalex +6 more sources
Frontiers in Microbiology, 2021 Introduction: Increasing number of deaths from multi-drug resistant bacterial infections has caused both the World Health Organization and the Centers for Disease Control and Prevention to repeatedly call for development of new, non-traditional ...
Marek Harhala +11 more
doaj +1 more source
Animal Models of Phage Therapy [PDF]
Frontiers in Microbiology, 2021 Amidst the rising tide of antibiotic resistance, phage therapy holds promise as an alternative to antibiotics. Most well-designed studies on phage therapy exist in animal models. In order to progress to human clinical trials, it is important to understand what these models have accomplished and determine how to improve upon them.
Samuel Penziner +3 more
openaire +4 more sources