Results 221 to 230 of about 114,190 (344)

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Evolving strategies of intracellular Hypervirulent <i>Klebsiella pneumoniae</i> during phage therapy: Reducing host autophagy and inflammation. [PDF]

Virulence
Chen H, Sun Y, Huang Z, Zhao D, Kong J, Chen H, Zhou C, Zhou T.   +7 more
europepmc   +1 more source

Effects of Increased Water Salinity and Temperature on the Development of Rainbow Trout Fry Syndrome (RTFS) Caused by Flavobacterium psychrophilum

Journal of Fish Diseases, EarlyView.
ABSTRACT Flavobacterium psychrophilum, the etiological agent of Rainbow Trout Fry Syndrome (RTFS) and Bacterial Coldwater Disease (BCWD), causes varying degrees of disease and mortality in salmonid aquaculture worldwide. Because its treatment relies on the use of antimicrobials, alternative interventions are of environmental and economic interest.
Valentina L. Donati, Niels Lorenzen, Lone Madsen   +2 more
wiley   +1 more source

Efficacy of phage therapy in controlling staphylococcal biofilms: a systematic review. [PDF]

Eur J Med Res
Mobarezi Z, Esfandiari AH, Abolbashari S, Meshkat Z.   +3 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Beware of host immune responses towards bacteriophages potentially impacting phage therapy. [PDF]

Vet Res
Démoulins T, Cherbuin JDR, Yimthin T, Eggerschwiler L, Adnan F, Jores J.   +5 more
europepmc   +1 more source

Experimental Phage Therapy for Burkholderia pseudomallei Infection

, 2016
Ong Guang-Han, Leang-Chung Choh, Kumutha Malar Vellasamy, Vanitha Mariappan, Li‐Yen Chang, Jamuna Vadivelu   +5 more
openalex   +2 more sources

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source

Current Applications and the Future of Phage Therapy for Periprosthetic Joint Infections. [PDF]

Antibiotics (Basel)
Abedi AO, Abedi AA, Ferry T, Citak M.
europepmc   +1 more source

Genomic Insights Into the Treponema Genus: Taxonomic Resolution of Treponema vincentii and Description of Two Novel Species, Treponema plautii sp. nov. and Treponema sinense sp. nov.

Molecular Oral Microbiology, EarlyView.
ABSTRACT Objectives Periodontal disease, a global health concern, is strongly associated with oral treponemes. However, the taxonomy of some species remains unresolved, hindering our understanding of their roles in disease. This study aims to clarify the taxonomy of three strains isolated from patients with periodontal disease using phylogenomic and ...
Jordan Y. H. Fong, Man Lung Yeung, Tsz Tuen Li, Wing Ho Li, Yuanchao Ma, Yan Zhao, Wai Keung Leung, Jade L. L. Teng   +7 more
wiley   +1 more source