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Phage Therapy in Veterinary Medicine [PDF]

open access: yesAntibiotics, 2021
To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects ...
Loponte R.   +3 more
openaire   +5 more sources

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

open access: yes, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]

open access: yes, 2016
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M   +5 more
core   +2 more sources

Phage Therapy in Germany—Update 2023 [PDF]

open access: yesViruses, 2023
Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current situation (2023) of applied phage therapy and supporting research in Germany. The authors, an interdisciplinary group working on patient-focused bacteriophage research, addressed phage production ...
Christian Willy   +19 more
openaire   +5 more sources

Phage Therapy in a 16-Year-Old Boy with Netherton Syndrome

open access: yesFrontiers in Medicine, 2017
Netherton syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial ...
Pikria Zhvania   +4 more
doaj   +1 more source

Bacteriophage as a potential therapy to control antibiotic-resistant Pseudomonas aeruginosa infection through topical application onto a full-thickness wound in a rat model

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Antibiotic-resistant Pseudomonas aeruginosa (P. aeruginosa) is one of the most critical pathogens in wound infections, causing high mortality and morbidity in severe cases.
Nouran Rezk   +9 more
doaj   +1 more source

Characterization of novel bacteriophages for biocontrol of bacterial blight in leek caused by Pseudomonas syringae pv. porri [PDF]

open access: yes, 2016
Pseudomonas syringae pv. porri, the causative agent of bacterial blight in leek (Allium porrum), is increasingly frequent causing problems in leek cultivation. Because of the current lack of control measures, novel bacteriophages were isolated to control
Anneleen eVolckaert   +16 more
core   +5 more sources

Bronisława Fejgin (1883–1943): Forgotten Important Contributor to International Microbiology and Phage Therapy

open access: yesAntibiotics, 2021
Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski   +4 more
doaj   +1 more source

Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections

open access: yesAntibiotics, 2021
Patients with chronic urinary and urogenital multidrug resistant bacterial infections received phage therapy (PT) using intravesical or intravesical and intravaginal phage administration.
Sławomir Letkiewicz   +5 more
doaj   +1 more source

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]

open access: yes, 2014
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong   +13 more
core   +1 more source

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