Results 21 to 30 of about 114,190 (344)

Phage Therapy in Veterinary Medicine [PDF]

Antibiotics, 2021
To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects ...
Loponte R., Pagnini U., Iovane G., Pisanelli G.   +3 more
openaire   +5 more sources

Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk

Biologics, 2021
Food safety is very important in the food industry as most pathogenic bacteria can cause food-borne diseases and negatively affect public health.
Abdallah S. Abdelsattar, Anan Safwat, Rana Nofal, Amera Elsayed, Salsabil Makky, Ayman El-Shibiny   +5 more
doaj   +1 more source

Phage Cocktails and the Future of Phage Therapy

Future Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade.
Benjamin K, Chan, Stephen T, Abedon, Catherine, Loc-Carrillo   +2 more
openaire   +2 more sources

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]

, 2016
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M, Bentayebi, K, Hajitou, A, Przystal, J, Suwan, K, Tsafa, E   +5 more
core   +2 more sources

Phage Therapy in a 16-Year-Old Boy with Netherton Syndrome

Frontiers in Medicine, 2017
Netherton syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial ...
Pikria Zhvania, Naomi Sulinger Hoyle, Lia Nadareishvili, Dea Nizharadze, Mzia Kutateladze   +4 more
doaj   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Bacteriophage as a potential therapy to control antibiotic-resistant Pseudomonas aeruginosa infection through topical application onto a full-thickness wound in a rat model

Journal of Genetic Engineering and Biotechnology, 2022
Background Antibiotic-resistant Pseudomonas aeruginosa (P. aeruginosa) is one of the most critical pathogens in wound infections, causing high mortality and morbidity in severe cases.
Nouran Rezk, Abdallah S. Abdelsattar, Doaa Elzoghby, Mona M. Agwa, Mohamed Abdelmoteleb, Rania G. Aly, Mohamed S. Fayez, Kareem Essam, Bishoy M. Zaki, Ayman El-Shibiny   +9 more
doaj   +1 more source

Phage therapy

Nature Reviews Methods Primers
Bacteriophage (phages) are viruses that exclusively use bacterial cells for propagation, killing the bacterial host in the process. In phage therapy, phages are used to reduce bacterial numbers, thereby curing bacterial infections. Although this principle is conceptually straightforward, its practical application faces several hurdles.
Mikael Skurnik, Sivan Alkalay-Oren, Maarten Boon, Martha Clokie, Thomas Sicheritz-Pontén, Krystyna Dąbrowska, Graham F. Hatfull, Ronen Hazan, Matti Jalasvuori, Saija Kiljunen, Rob Lavigne, Danish J. Malik, Ran Nir-Paz, Jean-Paul Pirnay   +13 more
  +9 more sources

Characterization of novel bacteriophages for biocontrol of bacterial blight in leek caused by Pseudomonas syringae pv. porri [PDF]

, 2016
Pseudomonas syringae pv. porri, the causative agent of bacterial blight in leek (Allium porrum), is increasingly frequent causing problems in leek cultivation. Because of the current lack of control measures, novel bacteriophages were isolated to control
Anneleen eVolckaert, Bart eDeclercq, Camille Nina Allonsius, Cinzia eVan Malderghem, Dieter eVandenheuvel, Ho Bin eJang, Jean Paul eNoben, Jochen eKlumpp, Johan eVan Vaerenbergh, Martine eMaes, Martine eMaes, Rob eLavigne, Sofie eRombouts, Sofie eRombouts, Sofie eVenneman, Yves eBriers, Yves eBriers   +16 more
core   +5 more sources

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]

, 2014
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong, Hu, Fuquan, Jin, Xiaolin, Le, Shuai, Li, Ming, Lu, Shuguang, Lux, Renate, Rao, Xiancai, Shi, Wenyuan, Tan, Yinling, Wang, Jing, Wu, Nicholas C, Yao, Xinyue, Zhao, Yan   +13 more
core   +1 more source