Results 21 to 30 of about 4,514,314 (397)
Phage therapy—constraints and possibilities
Upsala Journal of Medical Sciences, 2014 The rise of antibiotic-resistant bacterial strains, causing intractable infections, has resulted in an increased interest in phage therapy. Phage therapy preceded antibiotic treatment against bacterial infections and involves the use of bacteriophages, bacterial viruses, to fight bacteria.
Anders Nilsson
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Phage Therapy in the Management of Urinary Tract Infections: A Comprehensive Systematic Review
PHAGE, 2023 Urinary tract infections (UTIs) are a problem worldwide, affecting almost half a billion people each year. Increasing antibiotic resistance and limited therapeutic options have led to the exploration of alternative therapies for UTIs, including ...
A. M. Al-Anany +6 more
semanticscholar +1 more source
WikiJournal of Medicine, 2021 Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war.
Joana Azeredo +6 more
openaire +1 more source
Immunogenicity of Endolysin PlyC
Antibiotics, 2022 Endolysins are bacteriolytic enzymes derived from bacteriophages. They represent an alternative to antibiotics, since they are not susceptible to conventional antimicrobial resistance mechanisms.
Marek Adam Harhala +4 more
doaj +1 more source
Developing Phage Therapy That Overcomes the Evolution of Bacterial Resistance.
Annual Review of Virology, 2023 The global rise of antibiotic resistance in bacterial pathogens and the waning efficacy of antibiotics urge consideration of alternative antimicrobial strategies.
Agnès Oromí-Bosch +2 more
semanticscholar +1 more source
Translating phage therapy into the clinic: Recent accomplishments but continuing challenges
PLoS Biology, 2023 Phage therapy is a medical form of biological control of bacterial infections, one that uses naturally occurring viruses, called bacteriophages or phages, as antibacterial agents.
Aleksandra Petrović Fabijan +4 more
semanticscholar +1 more source
PhaTYP: Predicting the lifestyle for bacteriophages using BERT [PDF]
Briefings in Bioinformatics, November 2022, 2022 Bacteriophages (or phages), which infect bacteria, have two distinct lifestyles: virulent and temperate. Predicting the lifestyle of phages helps decipher their interactions with their bacterial hosts, aiding phages' applications in fields such as phage therapy.
arxiv +1 more source
Regulations of phage therapy across the world
Frontiers in Microbiology, 2023 Phage therapy, a century-long treatment targeting bacterial infection, was widely abandoned after the clinical availability of antibiotics in the mid-20th century. However, the crisis of antimicrobial resistance today led to its revival in many countries.
Qimao Yang +3 more
semanticscholar +1 more source
Open Forum Infectious Diseases, 2023 The use of bacteriophages (phages) is reemerging as a potential treatment option for antibiotic-resistant or nonresolving bacterial infections. Phages are bacteria-specific viruses that may serve as a personalized therapeutic option with minimal ...
H. Onallah +29 more
semanticscholar +1 more source
Two Newly Isolated Enterobacter-Specific Bacteriophages: Biological Properties and Stability Studies
Viruses, 2022 In an era of antibiotic therapy crisis caused by spreading antimicrobial resistance, and when recurrent urinary tract infections constitute a serious social and medical problem, the isolation and complex characterization of phages with a potential ...
Martyna Cieślik +5 more
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