Results 31 to 40 of about 90,396 (354)

Phage Therapy in a 16-Year-Old Boy with Netherton Syndrome

open access: yesFrontiers in Medicine, 2017
Netherton syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial ...
Pikria Zhvania   +4 more
doaj   +1 more source

Bacteriophage as a potential therapy to control antibiotic-resistant Pseudomonas aeruginosa infection through topical application onto a full-thickness wound in a rat model

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Antibiotic-resistant Pseudomonas aeruginosa (P. aeruginosa) is one of the most critical pathogens in wound infections, causing high mortality and morbidity in severe cases.
Nouran Rezk   +9 more
doaj   +1 more source

Bronisława Fejgin (1883–1943): Forgotten Important Contributor to International Microbiology and Phage Therapy

open access: yesAntibiotics, 2021
Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski   +4 more
doaj   +1 more source

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]

open access: yes, 2014
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong   +13 more
core   +1 more source

Phage Cocktails and the Future of Phage Therapy

open access: yesFuture Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade.
Stephen T. Abedon   +3 more
openaire   +3 more sources

Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections

open access: yesAntibiotics, 2021
Patients with chronic urinary and urogenital multidrug resistant bacterial infections received phage therapy (PT) using intravesical or intravesical and intravaginal phage administration.
Sławomir Letkiewicz   +5 more
doaj   +1 more source

Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages [PDF]

open access: yes, 2019
open access articlePurpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon.
Capparelli, Rosanna   +12 more
core   +2 more sources

Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]

open access: yes, 2012
UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles   +13 more
core   +2 more sources

Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses

open access: yesFrontiers in Immunology, 2023
Bacteriolytic enzymes are promising antibacterial agents, but they can cause a typical immune response in vivo. In this study, we used a targeted modification method for two antibacterial endolysins, Pal and Cpl-1. We identified the key immunogenic amino
Marek Adam Harhala   +14 more
doaj   +1 more source

Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? [PDF]

open access: yes, 2008
Antibody-based therapeutics currently enjoy unprecedented success, growth in research and revenues, and recognition of their potential. It appears that the promise of the "magic bullet" has largely been realized.
Dimitrov, Dimiter S, Marks, James D
core   +1 more source

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