Results 31 to 40 of about 4,551,719 (377)

Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2

open access: yesVirology Journal, 2023
Background Bacteriophages (phages) are one of the most promising alternatives to traditional antibiotic therapies, especially against multidrug-resistant bacteria.
Mohamed S. Fayez   +8 more
doaj   +1 more source

Phage Therapy as a Novel Therapeutic for the Treatment of Bone and Joint Infections.

open access: yesClinical Infectious Diseases, 2023
Solutions for bone and joint infection (BJI) are needed where conventional treatments are inadequate. Bacteriophages (phages) are naturally occurring viruses that infect bacteria and have been harnessed for refractory bone and joint infections (BJI) in ...
G. Suh, Tristan Ferry, M. Abdel
semanticscholar   +1 more source

Case report: Analysis of phage therapy failure in a patient with a Pseudomonas aeruginosa prosthetic vascular graft infection

open access: yesFrontiers in Medicine, 2023
Clinical case of a patient with a Pseudomonas aeruginosa multidrug-resistant prosthetic vascular graft infection which was treated with a cocktail of phages (PT07, 14/01, and PNM) in combination with ceftazidime-avibactam (CZA).
L. Blasco   +10 more
semanticscholar   +1 more source

Characterization of novel bacteriophages for biocontrol of bacterial blight in leek caused by Pseudomonas syringae pv. porri [PDF]

open access: yes, 2016
Pseudomonas syringae pv. porri, the causative agent of bacterial blight in leek (Allium porrum), is increasingly frequent causing problems in leek cultivation. Because of the current lack of control measures, novel bacteriophages were isolated to control
Anneleen eVolckaert   +16 more
core   +5 more sources

Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug‐resistant Burkholderia multivorans

open access: yesTransplant Infectious Disease, 2023
There is increased interest in bacteriophage (phage) therapy to treat infections caused by antibiotic‐resistant bacteria. A lung transplant recipient with cystic fibrosis and Burkholderia multivorans infection was treated with inhaled phage therapy for 7
G. Haidar   +15 more
semanticscholar   +1 more source

The Lytic Activity of Bacteriophage ZCSE9 against Salmonella enterica and Its Synergistic Effects with Kanamycin

open access: yesViruses, 2023
Salmonella, the causative agent of several diseases in humans and animals, including salmonellosis, septicemia, typhoid fever, and fowl typhoid, poses a serious threat to global public health and food safety. Globally, reports of therapeutic failures are
Abdallah S. Abdelsattar   +7 more
doaj   +1 more source

Fitness Trade-Offs between Phage and Antibiotic Sensitivity in Phage-Resistant Variants: Molecular Action and Insights into Clinical Applications for Phage Therapy

open access: yesInternational Journal of Molecular Sciences, 2023
In recent decades, phage therapy has been overshadowed by the widespread use of antibiotics in Western countries. However, it has been revitalized as a powerful approach due to the increasing prevalence of antimicrobial-resistant bacteria.
Jumpei Fujiki   +3 more
semanticscholar   +1 more source

Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]

open access: yes, 2020
Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia   +4 more
core   +1 more source

Improving phage therapy by evasion of phage resistance mechanisms

open access: yesJAC-Antimicrobial Resistance, 2023
Antibiotic failure is one of the most worrisome threats to global health. Among the new therapeutic efforts that are being explored, the use of bacteriophages (viruses that kill bacteria), also known as ‘phages’, is being extensively studied as a ...
I. Bleriot   +10 more
semanticscholar   +1 more source

Considerations for the Use of Phage Therapy in Clinical Practice

open access: yesAntimicrobial Agents and Chemotherapy, 2022
Increasing antimicrobial resistance and medical device-related infections have led to a renewed interest in phage therapy as an alternative or adjunct to conventional antimicrobials.
G. Suh   +23 more
semanticscholar   +1 more source

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