Results 41 to 50 of about 4,514,314 (397)

The Lytic Activity of Bacteriophage ZCSE9 against Salmonella enterica and Its Synergistic Effects with Kanamycin

Viruses, 2023
Salmonella, the causative agent of several diseases in humans and animals, including salmonellosis, septicemia, typhoid fever, and fowl typhoid, poses a serious threat to global public health and food safety. Globally, reports of therapeutic failures are
Abdallah S. Abdelsattar, Mohamed Atef Eita, Zainab K. Hammouda, Shrouk Mohamed Gouda, Toka A. Hakim, Aghapy Yermans Yakoup, Anan Safwat, Ayman El-Shibiny   +7 more
doaj   +1 more source

Phage Therapy as a Novel Therapeutic for the Treatment of Bone and Joint Infections.

Clinical Infectious Diseases, 2023
Solutions for bone and joint infection (BJI) are needed where conventional treatments are inadequate. Bacteriophages (phages) are naturally occurring viruses that infect bacteria and have been harnessed for refractory bone and joint infections (BJI) in ...
G. Suh, Tristan Ferry, M. Abdel
semanticscholar   +1 more source

Fitness Trade-Offs between Phage and Antibiotic Sensitivity in Phage-Resistant Variants: Molecular Action and Insights into Clinical Applications for Phage Therapy

International Journal of Molecular Sciences, 2023
In recent decades, phage therapy has been overshadowed by the widespread use of antibiotics in Western countries. However, it has been revitalized as a powerful approach due to the increasing prevalence of antimicrobial-resistant bacteria.
Jumpei Fujiki, Keisuke Nakamura, Tomohiro Nakamura, H. Iwano   +3 more
semanticscholar   +1 more source

Considerations for the Use of Phage Therapy in Clinical Practice

Antimicrobial Agents and Chemotherapy, 2022
Increasing antimicrobial resistance and medical device-related infections have led to a renewed interest in phage therapy as an alternative or adjunct to conventional antimicrobials.
G. Suh, T. Lodise, P. Tamma, Jane M. Knisely, J. Alexander, S. Aslam, Karen D. Barton, Erica Bizzell, Katherine M. C. Totten, Joseph Campbell, B. Chan, S. Cunningham, K. Goodman, K. Greenwood-Quaintance, A. Harris, Shayla E Hesse, A. Maresso, V. Nussenblatt, D. Pride, M. Rybak, Zoe M. Sund, D. van Duin, D. Van Tyne, Robin Patel   +23 more
semanticscholar   +1 more source

Unexploited opportunities for phage therapy [PDF]

Frontiers in Pharmacology, 2015
Project “BioHealth - Biotechnology and Bioengineering approaches to improve health quality,” Ref. NORTE-07-0124-FEDER-000027, co-funded by the Programa Operacional Regional do Norte (ON.2 – O Novo Norte), QREN, FEDER. Project “Consolidating Research Expertise and Resources on Cellular and Molecular Biotechnology at CEB/IBB,” Ref.
Oliveira, Hugo Alexandre Mendes, Sillankorva, Sanna, Merabishvili, Maia, Kluskens, Leon, Azeredo, Joana   +4 more
openaire   +5 more sources

Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]

, 2020
Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia, Tavanti, Arianna, Tkhilaishvili, Tamta, Trampuz, Andrej, Wang, Lei   +4 more
core   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease

Clinical Infectious Diseases, 2022
Background Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus, are increasingly common among patients with cystic fibrosis and chronic bronchiectatic lung diseases.
R. Dedrick, Bailey E. Smith, Madison Cristinziano, K. Freeman, D. Jacobs-Sera, Y. Belessis, A. Whitney Brown, K. Cohen, R. Davidson, D. van Duin, Andrew B. Gainey, Cristina Berastegui Garcia, C. R. Robert George, G. Haidar, Winnie Ip, J. Iredell, A. Khatami, J. Little, Kirsi Malmivaara, B. McMullan, D. Michalik, A. Moscatelli, J. Nick, M. G. Tupayachi Ortiz, H. Polenakovik, P. Robinson, M. Skurnik, D. Solomon, J. Soothill, H. Spencer, P. Wark, A. Worth, R. Schooley, C. Benson, G. Hatfull   +34 more
semanticscholar   +1 more source

Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk

Biologics, 2021
Food safety is very important in the food industry as most pathogenic bacteria can cause food-borne diseases and negatively affect public health.
Abdallah S. Abdelsattar, Anan Safwat, Rana Nofal, Amera Elsayed, Salsabil Makky, Ayman El-Shibiny   +5 more
doaj   +1 more source

Bacteriophage classification for assembled contigs using Graph Convolutional Network [PDF]

Bioinformatics, Volume 37, Issue Supplement1, July 2021, Pages 25-33, 2021
Motivation: Bacteriophages (aka phages), which mainly infect bacteria, play key roles in the biology of microbes. As the most abundant biological entities on the planet, the number of discovered phages is only the tip of the iceberg. Recently, many new phages have been revealed using high throughput sequencing, particularly metagenomic sequencing ...
arxiv   +1 more source