Results 61 to 70 of about 72,592 (256)

Can phage–antibiotic combinations overcome uropathogenic Escherichia coli regrowth? evidence from in vitro and in vivo models

Virology Journal
Phage therapy is currently gaining attention as a promising alternative for treating multi-drug resistant (MDR) bacterial infections, including urinary tract infections (UTIs).
Salsabil Makky, Assmaa H. Hussein, Amira A. Mohamed, Kareem Essam, Mona M. Agwa, Marwa M. Abd ElAziz, Ayman El-Shibiny   +6 more
doaj   +1 more source

Perception of phage therapy and research across selected professional and social groups in Poland

Frontiers in Public Health
There is no doubt that in the last 15 years phage therapy has re-emerged from the shadow of antibiotics, from the perspective of both scientists and various patient advocacy groups.
Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki   +8 more
doaj   +1 more source

Editorial: Phage Biology and Phage Therapy

Frontiers in Microbiology, 2022
Shuai Le, Xuesong He, Xuesong He, Yigang Tong   +3 more
openaire   +3 more sources

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University

Scientific Reports
Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent bacterial infections, and the year 2021 marked the centennial of Felix d’Hérelle’s first publication on the clinical applications of phages.
Silvia Würstle, Alina Lee, Kaitlyn E. Kortright, Franziska Winzig, William An, Gail L. Stanley, Govindarajan Rajagopalan, Zach Harris, Ying Sun, Buqu Hu, Michael Blazanin, Maryam Hajfathalian, Paul L. Bollyky, Paul E. Turner, Jonathan L. Koff, Benjamin K. Chan   +15 more
doaj   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Phage vB_Ec_ZCEC14 to treat antibiotic-resistant Escherichia coli isolated from urinary tract infections

Virology Journal
Escherichia coli is a commensal bacterial species in the human gastrointestinal tract; however, it could be pathogenic and cause severe infections in intra and extra-intestinal sites. Uropathogenic E.
Nedaa M. Ismael, Mohamed Azzam, Mohamed Abdelmoteleb, Ayman El-Shibiny   +3 more
doaj   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Molecular Evaluation of High Fluoroquinolone Resistant Genes in Endemic Cases of Shigellosis, Northeast Part of Karnataka, India

Annals of Global Health, 2017
ObjectivesShigellosis is an acute infection of the intestine caused by bacteria in the genus 'Shigella' and also an important cause of diarrhea in developing countries.
Prabhurajeshwar C, Pramod Desai, Kelmani Chandrakanth R   +2 more
doaj   +1 more source