Results 71 to 80 of about 2,471,270 (185)

Phage therapy for Escherichia coli urinary tract infections: selecting therapeutic phages and understanding resistance mechanisms in urine [PDF]

open access: yes
Urinary tract infections (UTIs) affect a large proportion of the human and canine population. Due to rising levels of antibiotic resistance, empirical treatment with conventional antibiotics may fail, which can increase the probabilities of recurrence ...
Park de la Torriente, Alba
core   +1 more source

Physicochemical and Proteolytic Barriers Limiting Activity of Cpl-1 and Pal Endolysins in Human Circulation

open access: yesCurrent Issues in Molecular Biology
The growing prevalence of antibiotic-resistant bacterial infections poses a serious burden on healthcare systems worldwide. Endolysins are promising candidates for a new type of antibiotic due to their strong bacteriolytic activity.
Marek Adam Harhala   +5 more
doaj   +1 more source

Characterization and therapeutic potential of phage vB_Eco_ZCEC08 against multidrug-resistant uropathogenic Escherichia coli

open access: yesBMC Microbiology
Background Urinary tract infections (UTIs) caused by antibiotic-resistant bacteria have become a significant public health concern. The increasing ineffectiveness of antibiotics has led to a renewed focus on investigating other strategies, such as ...
Assmaa H. Hussein   +4 more
doaj   +1 more source

Phage Therapy and Phage Engineering technologies for tackling Antibiotic-Resistance in Bacterial Infections

open access: yes
openIn recent years, the escalating crisis of antibiotic resistance has spurred the search for alternative antimicrobial strategies, with bacteriophage therapy emerging as a promising candidate.
ORLANDI, SIMONE
core  

Using millimeter‐waves for rapid detection of pathogenic bacteria in food based on bacteriophage

open access: yesEngineering Reports, 2019
The accessibility of a rapid method for detection and identification of food‐borne pathogens is crucial for food industry worldwide. Antibiotic resistance bacteria (eg, E. coli) that can enter the food chain in different ways, can indeed survive on foods
Kamel S. Sultan   +3 more
doaj   +1 more source

Efficacy of phage vB_Ps_ZCPS13 in controlling Pan-drug-resistant Pseudomonas aeruginosa from urinary tract infections (UTIs) and eradicating biofilms from urinary catheters

open access: yesVirology Journal
Background Pan-drug resistance (PDR) is a ticking time bomb, as it causes high human hospitalizations and mortality rates. For instance, Pseudomonas aeruginosa is associated with significant rates of urinary tract infections (UTIs) due to several reasons
Amira A. Mohamed   +2 more
doaj   +1 more source

In vitro and in vivo evaluation of the biofilm-degrading Pseudomonas phage Motto, as a candidate for phage therapy [PDF]

open access: yes
Infections caused by Pseudomonas aeruginosa are becoming increasingly difficult to treat due to the emergence of strains that have acquired multidrug resistance.
Elangovan, Namasivaysam   +17 more
core   +1 more source

In Vivo Emergence of Podovirus Resistance via tarS Mutation During Phage-Antibiotic Treatment of Experimental MSSA Endocarditis

open access: yesViruses
Phage therapy shows promise as an adjunct to antibiotics for treating Staphylococcus aureus infections. We previously reported a combined flucloxacillin/two-phage cocktail treatment selected for resistance to podovirus phage 66 in a rodent model of ...
Jérémy Cherbuin   +3 more
doaj   +1 more source

Dual Nature of Bacteriophages: Friends or Foes in Minimally Processed Food Products—A Comprehensive Review

open access: yesViruses
The increasing consumer demand for minimally processed foods (MPFs) has highlighted the need for innovative preservation methods that ensure both safety and quality.
Michał Wójcicki   +3 more
doaj   +1 more source

Efficacy of φkm18p phage therapy in a murine model of extensively drug-resistant Acinetobacter baumannii infection

open access: yes, 2018
Jiun-Ling Wang,1,* Chih-Feng Kuo,2,* Che-Ming Yeh,3 Jung-Ren Chen,4 Ming-Fang Cheng,5–7 Chih-Hsin Hung3 1Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan ...
Yeh CM   +5 more
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