Results 41 to 50 of about 41,388 (353)

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]

, 2014
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
A McKenna, A Stamatakis, B Langmead, B López, B Tessema, CB Ford, D Stucki, DR Zerbino, E Abadia, F Coll, F Coll, G Thwaites, H Li, H Zhang, I Comas, I Filliol, J Felsenstein, J Wang, JH Bates, M Caws, M Kato-Maeda, M Kato-Maeda, N Casali, P Nahid, PF Barnes, PL Lin, R Firdessa, S Feuerriegel, S Gagneux, S Homolka, T Derrien, T Weniger, TA Rado, Y Blouin   +33 more
core   +2 more sources

Phenotyping and genotyping methods applied to investigate the relatedness of Brazilian isolates of Enterobacter cloacae

Brazilian Journal of Medical and Biological Research, 1999
In order to evaluate the resolving power of several typing methods to identify relatedness among Brazilian strains of Enterobacter cloacae, we selected twenty isolates from different patients on three wards of a University Hospital (Orthopedics ...
A.L.C. Darini, V.D. Magalhães, C.L. Levy, A.L. Barth, A.L. Coscina   +4 more
doaj   +1 more source

Campylobacter jejuni Developed the Resistance to Bacteriophage CP39 by Phase Variable Expression of 06875 Encoding the CGPTase

Viruses, 2022
Bacteriophage (phage) is regarded as an antimicrobial alternative for Campylobacter in food production. However, the development of phage resistance to the host is a main concern for the phage application.
Yuanyue Tang, Jie Li, Yuexuan Wang, Zhaojun Song, Hangning Ying, Linghua Kong, Xin’an Jiao, Jinlin Huang   +7 more
doaj   +1 more source

Ribosomal RNA Gene Restriction Patterns Provide Increased Sensitivity for Typing Salmonella typhi Strains [PDF]

, 2017
To date, epidemiologic associations among strains of Salmonella typhi are based exclusively on phage typing, which may be of limited value if a common phage type is involved.
Altwegg, M., Farmer III, J. J., Hickman-Brenner, F. W.   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The epidemiological type identification of Serratia marcescens from outbreaks of infection in hospitals [PDF]

, 2017
A study of serological, bacteriocine and phage typing of Serratia marcescens was made. Specific O-antisera of adequate titre were relatively simple to prepare but H-antisera exhibited many heterologous agglutination reactions amongst the type strains ...
Bucher, C., Erdman, Y. J., Pitt, T. L.
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Northern Normal: Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939–2000)

Engaging Science, Technology, and Society
Bacteriophage-typing – using bacterial viruses to identify bacteria at the species and strain level – was the gold standard technology underlying the rapid expansion of international surveillance for major bacterial pathogens after 1945.
Claas Kirchhelle, Charlotte Kirchhelle
doaj   +1 more source

Phage-Typing Of Coagulase-Negative Staphylococci [PDF]

Journal of Medical Microbiology, 1972
THE clinical importance of infection with coagulase-negative staphylococci (Staphylococcus epidermidis) is increasing (Quinn, Cox and Drake, 1966; Verhoef, 1970). Strains isolated from patients with endocarditis or colonisation of Spitz-Holter valves often belong to biotype I in Baird-Parker’s scheme (Holt, 1969), and seem to be different in their ...
J, Verhoef, C P, Van Boven, K C, Winkler
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source