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Phage and defective phage of strains of Myxococcus

Archives of Microbiology, 1976
1. Phage-like particles were found in the supernatants of cultures of strains of Myxococcus xanthus, M. virescens and M. fulvus. The largest number of such particles was associated with M. virescens V2. Most of the particles were similar in morphology to the virulent Myxococcus phage, MX-1. 2.
N L, Brown   +5 more
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Phage-Phage Interactions

2020
Often considered to be the most numerous and most diverse biological entities, phages are relatively simple forms of life. Despite this, phages have remarkably similar behaviors to those characterized in more complex organisms. When considering the biological development of phages from this perspective, new ideas and narratives can be explored to ...
Jimmy T. Trinh, Lanying Zeng
openaire   +1 more source

Phage therapy

Drug Discovery Today, 2009
There is a renaissance of interest in the antimicrobial potential of phages as more pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is important to ask why it is not part of the current repertoire of western medicine despite the fact that it has been continuously and extensively used in Eastern Europe for ...
John N, Housby, Nicholas H, Mann
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Jumbo phages

Current Biology, 2023
In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding   +2 more
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Phage-Phage, Phage-Bacteria, and Phage-Environment Communication

2020
Besides obtaining and utilizing resources, organisms have three basic ecological tasks: to survive, to reproduce, and to move. Survival is necessary for reproduction, reproduction increases numbers, and movement at a minimum assures that all of an organism’s ‘eggs’ are not found in the same spatial ‘basket’.
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Phage presentation

Molecular Microbiology, 1996
SummaryThere has recently been great interest in the use of the filamentous bacteriophage fd as a vehicle for the display of peptides and proteins. Phage libraries displaying random peptides up to 38 amino acids in length can be used (i) to select for ligands able to bind specific target molecules; (ii) to mimic non‐proteinaceous ligands; and (iii) as ...
H R, Hill, P G, Stockley
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Phage Typing

2009
Phage typing is a rapid, economical, reliable, and reproducible technique, requiring no specialized equipment, for fingerprinting disease-causing agents for epidemiological investigation and surveillance.
Irina, Chirakadze   +2 more
openaire   +2 more sources

Intra-phage immunity: Set a (pro)phage to catch a phage

Cell Host & Microbe
In this issue, Brenes and Laub screen temperate phages for defenses against other temperate phages. This uncovers an array of prophage-encoded immune systems in E. coli. The work expands the concept of phage-phage conflict, reveals context dependency of defense, and highlights temperate phages as both targets and carriers of anti-phage immunity.
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Synthetic phage and its application in phage therapy

2023
Synthetic phage analysis has been implemented in progressive various areas of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been altered for developing gene circuits to program biological systems.
Ajay, Kumar, Anuj, Yadav
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Phage Display

2012
Phage display has emerged as one of the leading technologies for the selection and generation of highly specific antibodies, offering a number of advantages over traditional ways of antibody generation such as mouse hybridoma techniques. While there are various possibilities to conduct phage display, selection of antibodies via solution panning is an ...
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