Results 21 to 30 of about 33,934 (266)

Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages

open access: yesFrontiers in Immunology, 2021
Phagocytosis is an essential process for the uptake of large (>0.5 µm) particulate matter including microbes and dying cells. Specialized cells in the body perform phagocytosis which is enabled by cell surface receptors that recognize and bind target ...
Yan Lin Fu   +3 more
doaj   +1 more source

Brain Abscess as Severe Presentation of Specific Granule Deficiency

open access: yesFrontiers in Pediatrics, 2020
Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule ...
Maria Leszcynska   +9 more
doaj   +1 more source

LC3-Associated Phagocytosis in Bacterial Infection

open access: yesPathogens, 2022
LC3-associated phagocytosis (LAP) is a noncanonical autophagy process reported in recent years and is one of the effective mechanisms of host defense against bacterial infection. During LAP, bacteria are recognized by pattern recognition receptors (PRRs),
Jin Yuan   +4 more
doaj   +1 more source

Spontaneously Occurring Small-Colony Variants of Staphylococcus aureus Show Enhanced Clearance by THP-1 Macrophages

open access: yesFrontiers in Microbiology, 2020
Staphylococcus aureus is a common cause of chronic and relapsing infection, especially when the ability of the immune system to sterilize a focus of infection is compromised (e.g., because of a foreign body or in the cystic fibrosis lung).
Simon M. Stoneham   +5 more
doaj   +1 more source

Mechanisms and roles of phagocytosis in Drosophila and Caenorhabditis elegans [PDF]

open access: yesInvertebrate Survival Journal, 2007
Our understanding of the humoral immune response in both vertebrates and invertebrates has dramatically deepened in the past decade. In contrast, many of the mechanisms and roles of the cellular immune response remain to be elucidated. Phagocytosis is at
Y Nakanishi, A Shiratsuchi
doaj  

Diversity and Versatility of Phagocytosis: Roles in Innate Immunity, Tissue Remodeling, and Homeostasis

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role in innate immunity by eliminating pathogenic bacteria,
Justin J. Lim   +4 more
doaj   +1 more source

Phagocytes and the Lung [PDF]

open access: yesAnnals of the New York Academy of Sciences, 1997
Activation of lung phagocytes, whether involving residential or recruited phagocytic cells (macrophages, monocytes, neutrophils), results in a series of products important for development of inflammatory injury of the lung. An understanding of the mechanisms of cell activation as well as how products of these activated cells interact with cellular and ...
openaire   +3 more sources

Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes

open access: yesFrontiers in Immunology, 2022
Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps ...
Eshraq Tantawy   +10 more
doaj   +1 more source

The Application of Organotypic Brain Slice Culture to Study Microglial Differentiation by Lycopersicon esculentum and Sambucus nigra Lectin Histochemistry [PDF]

open access: yesJournal of Cell and Molecular Research, 2014
Microglia cells are a subset of central nervous system (CNS) macrophages. Changes in the CNS such as injury, or developmental events, follow by morphological and physiological changes in microglia cells.
Roya Lari, Peter Kitchener
doaj   +1 more source

“Stimulate the Phagocyte”: Contested Terrains and the Birth of Cellular Immunity in turn-of-the-century Paris

open access: yesArts et Savoirs, 2022
This article traces the imaginative and linguistic work at play in the history of immunity from late nineteenth to early twentieth century France, culminating with Elie Metchnikoff, the “father” of immunology, and his discovery, the phagocyte ...
Loren K. Wolfe
doaj   +1 more source

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