Results 141 to 150 of about 219,803 (412)

Immunomodulatory effects of herbal plants plus melatonin on human blood phagocytes [PDF]

, 2010
It has been shown a mixture of seven herbal plants was able to trigger cell oxidative mechanism and subsequently inducing cellular activation. Moreover, melatonin hormone has also been shown to perform different actions on the cellular oxidative ...
Adenilda Cristina Honorio-França, Carlos Kusano Bucalen Ferrari, Claudemir Batalini, Eduardo Luzia França, Joanna Conde Maynié, Uender Correia Rodrigues Pereira, Valéria Conde Correa   +6 more
core   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Microglial/macrophage activation in the cerebrospinal fluid of neuromyelitis optica spectrum disorders

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Aim The aims of this pilot study were to investigate the levels of biomarkers of microglial/macrophage activation—YKL‐40, sCD163, and sCD14—in patients with neuromyelitis optica spectrum disorder (NMOSD) and determine the possible associations between these biomarkers and Expanded Disability Status Scale (EDSS) scores.
Jinghong Li, Yan He, Honghao Wang, Jinyu Chen   +3 more
wiley   +1 more source

Age-related changes of arginase activity and nitric oxide level in phagocytes and their modulation by thymic mesenchymal stromal cells

Біологічні студії, 2017
Arginine metabolism plays an important role in the activation of phagocytes, which are responsible for initiation, regulation, and resolution of inflammation.
R. S. Dovhyi, I. S. Nikolsky, L. M. Skivka   +2 more
doaj   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

ROS production in phagocytes: why, when, and where?

Journal of Leukocyte Biology, 2013
In the phagocytosis field, ROS production by the phagocyte NOX has been associated with pathogen killing for the last 50 years. Since the discovery of nonphagocyte NOX, numerous other roles for ROS production have been identified.
S. Dupré-Crochet, Marie Erard, O. Nüβe   +2 more
semanticscholar   +1 more source

Extravasation of Borrelia burgdorferi Across the Blood–Brain Barrier is an Extremely Rare Event

Advanced Science, EarlyView.
Lyme disease is caused by vascular dissemination of the bacteria Borrelia. In a 3D tissue‐engineered microvessel model, Borrelia extravasation across the blood–brain barrier is extremely rare, implying that neuroborreliosis is not caused via direct cytotoxicity.
Linus Wang, Zikai Xia, Anjan Singh, Bhavna Murarka, Nicole Baumgarth, John N. Aucott, Peter C. Searson   +6 more
wiley   +1 more source

Tumor‐associated macrophages regulate the function of cytotoxic T lymphocyte through PD‐1/PD‐L1 pathway in multiple myeloma

Cancer Medicine, Volume 11, Issue 24, Page 4838-4848, December 2022., 2022
Tumor‐associated macrophages(TAMs) are a vital constituent of the tumor microenvironment and involved in the immunological escape of vicious clonal plasma cells of myeloma patients. Our research shows that CSF1R can regulates the production of TAMs while the PD‐1/PD‐L1 pathway regulates the effect of TAMs on cytotoxic T lymphocyte. It may provide a new
Jiangbo Zhang, Zhaoyun Liu, Panpan Cao, Hao Wang, Hui Liu, Luoming Hua, Hua Xue, Rong Fu   +7 more
wiley   +1 more source

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators.

Blood, 2012
Phagocytes orchestrate acute inflammation and host defense. Here we carried out lipid mediator (LM) metabololipidomics profiling distinct phagocytes: neutrophils (PMN), apoptotic PMN, and macrophages.
Jesmond Dalli, C. Serhan
semanticscholar   +1 more source

The avian lung-associated immune system [PDF]

, 2006
The lung is a major target organ for numerous viral and bacterial diseases of poultry. To control this constant threat birds have developed a highly organized lung-associated immune system.
Dalamani, Grammatia, Kaspers, Bernd, Reese, Sven   +2 more
core   +3 more sources