Results 11 to 20 of about 219,012 (412)

EFFECT OF INTRACRANIAL CATHETER PLACEMENT ON MICROGLIA METABOLIC PROFILE OF RATS [PDF]

open access: yesBiotechnologia Acta, 2018
The aim of the work was to investigate the effect of the intracranial catheter placement on the metabolic profile of rat microglia. Microglial cells were isolated by the centrifugation in Percoll gradient.
Y. Hurmach   +3 more
doaj   +1 more source

A hitchhiker's guide to myeloid cell subsets: practical implementation of a novel mononuclear phagocyte classification system [PDF]

open access: yes, 2015
The classification of mononuclear phagocytes as either dendritic cells or macrophages has been mainly based on morphology, the expression of surface markers, and assumed functional specialization.
Adams   +123 more
core   +7 more sources

Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis

open access: yesFrontiers in Immunology, 2021
The mechanisms that lead to disease onset and propagation in patients with chronic rhinosinusitis (CRS) are not fully elucidated. Maresins (MaR) are a family of essential fatty acid-derived lipid mediators that play a central role in the regulation of ...
Issa Beegun   +4 more
doaj   +1 more source

Phagocyte Chemoattraction Is Induced through the Mcp-1–Ccr2 Axis during Efferocytosis

open access: yesCells, 2021
Apoptotic cells generated during development and for tissue homeostasis are swiftly and continuously removed by phagocytes via a process called efferocytosis.
Sang-Ah Lee   +9 more
doaj   +1 more source

Pleiotropic effects of PPAR-α – from benchside to bedside

open access: yesМедицинская иммунология, 2021
Here we review literature data on properties of a member of nuclear hormone receptors - peroxisome proliferator-activated receptor-α. It was shown that PPARα was expressed on different cells including dendritic cells, macrophages, B- and T-cells.
I. V. Shirinsky, V. S. Shirinsky
doaj   +1 more source

The Diverse Roles of Phagocytes During Bacterial and Fungal Infections and Sterile Inflammation: Lessons From Zebrafish

open access: yesFrontiers in Immunology, 2020
The immediate and natural reaction to both infectious challenges and sterile insults (wounds, tissue trauma or crystal deposition) is an acute inflammatory response. This inflammatory response is mediated by activation of the innate immune system largely
Tanja Linnerz, Christopher J. Hall
doaj   +1 more source

A mouse ear skin model to study the dynamics of innate immune responses against the microsporidian Encephalitozoon cuniculi

open access: yesFrontiers in Microbiology, 2023
Microsporidia are obligate intracellular parasites related to fungi that cause severe infections in immunocompromised individuals. Encephalitozoon cuniculi is a microsporidian species capable of infecting mammals, including human and rodents. In response
Eugénie Carriere   +5 more
doaj   +1 more source

Immunological mechanisms involved in macrophage activation and polarization in schistosomiasis

open access: yesParasitology, 2023
Human schistosomiasis is caused by helminths of the genus Schistosoma. Macrophages play a crucial role in the immune regulation of this disease. These cells acquire different phenotypes depending on the type of stimulus they receive.
Irlla Correia Lima Licá   +10 more
doaj   +1 more source

Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice

open access: yesNature Communications, 2022
Microglia are professional phagocytes in the CNS. However, which cells scavenge corpses of microglia is largely neglected. Peng and colleagues found that nonprofessional phagocytes (astrocyte) phagocytose the debris of professional phagocytes (microglia).
Tian Zhou   +22 more
doaj   +1 more source

The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism.
Aryashree Arunima   +2 more
doaj   +1 more source

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