Results 11 to 20 of about 235,236 (395)

Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis

Cardiovascular Research, 2022
Aims Accumulation of mononuclear phagocytes [monocytes, macrophages, and dendritic cells (DCs)] in the vessel wall is a hallmark of atherosclerosis. Using integrated single-cell analysis of mouse and human atherosclerosis, we here aimed to refine the ...
A. Zernecke, Florian Erhard, Tobias Weinberger, C. Schulz, K. Ley, A. Saliba, C. Cochain   +6 more
semanticscholar   +1 more source

TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination

Journal of Experimental Medicine, 2021
Remyelination requires the clearance of cholesterol-rich myelin debris within demyelinating lesions by phagocytes. Gouna et al. found that TREM2-dependent formation of lipid droplets is necessary to buffer excess lipids released by myelin injury and ...
Garyfallia Gouna, C. Klose, Mar Bosch-Queralt, Lu Liu, O. Gokce, Martina Schifferer, Ludovico Cantuti-Castelvetri, M. Simons   +7 more
semanticscholar   +1 more source

Influencе of peptides from the bursa of Fabricius in broiler chickens on the functional activity of subpopulations of lymphocytes in immunosuppressed mice

Теория и практика переработки мяса, 2022
It is known that peptides inhibit the enzymes of viruses and are able to penetrate into cells by their embedding in the cell membrane, as a result of which the penetration of viruses into the host cell is blocked, which makes it possible to consider ...
N. A. Kolberg, S. L. Tikhonov, N. V. Tikhonova, L. S. Kudryashov   +3 more
doaj   +1 more source

A mouse ear skin model to study the dynamics of innate immune responses against the microsporidian Encephalitozoon cuniculi

Frontiers in Microbiology, 2023
Microsporidia are obligate intracellular parasites related to fungi that cause severe infections in immunocompromised individuals. Encephalitozoon cuniculi is a microsporidian species capable of infecting mammals, including human and rodents. In response
Eugénie Carriere, Aizat Iman Abdul Hamid, Inès Feki, Aurore Dubuffet, Frédéric Delbac, Pascale Gueirard   +5 more
doaj   +1 more source

Interleukin-4 during post-exercise recovery negatively correlates with the production of phagocyte-generated oxidants

Frontiers in Physiology, 2023
Exhaustive run induced a biphasic oxidative response of circulating phagocytes in 16 amateur sportsmen. The first phase involved an increment just after exercise of enhanced whole blood chemiluminescence normalized per phagocyte count, whereas in the ...
Adam Chmielecki, Krzysztof Bortnik, Szymon Galczynski, Karolina Kopacz, Gianluca Padula, Hanna Jerczynska, Robert Stawski, Dariusz Nowak   +7 more
doaj   +1 more source

Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

bioRxiv, 2020
Phagocytes engulf unwanted particles into phagosomes that then fuse with lysosomes to degrade the enclosed particles. Ultimately, phagosomes must be recycled to help recover membrane resources that were consumed during phagocytosis and phagosome ...
C. Lancaster, Aaron Fountain, R. Dayam, Elliott Somerville, J. Sheth, V. Jacobelli, Alex Somerville, M. Terebiznik, R. Botelho   +8 more
semanticscholar   +1 more source

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity

Frontiers in Immunology, 2019
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques.
Alwin Kamermans, Merel Rijnsburger, Ananya Chakraborty, Susanne van der Pol, Helga E. de Vries, Jack van Horssen   +5 more
doaj   +1 more source

New Data on the Rhamnose-Binding Lectin from the Colonial Ascidian Botryllus schlosseri: Subcellular Distribution, Secretion Mode and Effects on the Cyclical Generation Change

Marine Drugs, 2023
Botryllus schlosseri in a cosmopolitan ascidian, considered a reliable model organism for studies on the evolution of the immune system. B. schlosseri rhamnose-binding lectin (BsRBL) is synthesised by circulating phagocytes and behaves as an opsonin by ...
Giacomo Bovo, Loriano Ballarin
doaj   +1 more source

Comparison of immune parameters in cows with normal and prolonged involution time of uterus

Veterinární Medicína, 2002
Indices of cellular immunity in postpartum Holsteincows with the normal (n = 9) and prolonged (n = 4) uterine involution time were evaluated. Peripheral white blood cells were isolated by lysis from postpartum animals.
M. Levkut, J. Pistl, V. Revajová, J. Chroma, M. Levkutová, V. Dávid   +5 more
doaj   +1 more source