Results 231 to 240 of about 235,236 (395)

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

Elementary immunology [PDF]

open access: yes, 2017
Gogolák, Péter, Koncz, Gábor
core  

Anti-Pseudomonas aeruginosaIgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils [PDF]

open access: bronze, 2016
Kim Thomsen   +5 more
openalex   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang   +6 more
wiley   +1 more source

Metabolic reprogramming in efferocytosis. [PDF]

open access: yesFront Cell Dev Biol
Yan Q   +6 more
europepmc   +1 more source

The phagocytic state of brain myeloid cells after ischemia revealed by superresolution structured illumination microscopy [PDF]

open access: gold, 2019
Stefano Fumagalli   +6 more
openalex   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang   +14 more
wiley   +1 more source

Sacrificing cells of the cyst: non-apoptotic cell death in germline cysts via acidification. [PDF]

open access: yesFront Cell Death
Bandyadka S   +4 more
europepmc   +1 more source

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