Results 241 to 250 of about 235,236 (395)

Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.

Advances in Experimental Medicine and Biology, 2016
Aaron M Fond, K. Ravichandran
semanticscholar   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Histones present on the surface of late apoptotic cells induce RAGE-mediated phagocytosis. [PDF]

Cell Commun Signal
Li Y, Zhou X, Yang Y, Du C, Liu YS, Li Z, Zhang L, Nakanishi H.   +7 more
europepmc   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Early responses of primary human and bovine monocytes, monocytic THP-1 cells and THP-1 cell-derived macrophages to vital <i>Toxoplasma gondii</i> tachyzoites. [PDF]

Front Immunol
Hanke D, Velásquez ZD, Büttner K, Krueger A, Ross R, Hecker A, Mazurek S, Grau V, Taubert A, Hermosilla C, Richter K, Conejeros I.   +11 more
europepmc   +1 more source

Changes in the Phagocytic Activity of Polymorphonuclear Leukocytes following Total Body X-Irradiation in the Rat [PDF]

, 1954
M. Wilkinson
openalex   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Radial astroglia cooperate with microglia to clear neuronal cell bodies during zebrafish optic tectum development. [PDF]

Cell Rep
Barber HM, Robbins CG, Cutler Z, Brown RI, Jung LE, Werkman I, Kucenas S.   +6 more
europepmc   +1 more source

Melanoma goes on a diet to get moving: toning down phagocytic Rab7 expression helps melanoma to metastasise

, 2014
Alistair N. Hume, Miguel C. Seabra
openalex   +2 more sources

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source