Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
llluminating the live-cell dynamics of early interactions between neutrophils and the microsporidian parasite Encephalitozoon cuniculi. [PDF]
Carriere E +6 more
europepmc +1 more source
Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho +27 more
wiley +1 more source
Graduate-level medical doctors in Uganda have limited awareness of warning, specific signs, and immunological investigations of primary immunodeficiencies. [PDF]
Sande OJ, Matovu B, Kongai T, Olobo J.
europepmc +1 more source
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger +28 more
wiley +1 more source
Bcl-2-Dependent Persistence of Mononuclear Phagocytes Promotes Ocular Fibrosis. [PDF]
Song YS +4 more
europepmc +1 more source
Single-Cell Transcriptomics Reveals CCL3<sup>+</sup> Classical Monocyte Subset Linked to Autoimmune Pathogenesis. [PDF]
Xu H +9 more
europepmc +1 more source
Identification of key genes related to metabolic cell death in hepatic ischemia-reperfusion injury from transcriptome data and mechanism research using single-cell data. [PDF]
Yu H, Cao Y, Wang J, Weng X, Xu W.
europepmc +1 more source
Evolutionary conservation and divergence of phagocytic and coagulation programs across bilaterian circulating immune cells. [PDF]
Li Y +28 more
europepmc +1 more source

