Results 41 to 50 of about 219,012 (412)

CFTR Modulators Dampen Aspergillus-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes

Frontiers in Cellular and Infection Microbiology, 2020
Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A.
Alexander J. Currie, Alexander J. Currie, Ellen T. Main, Heather M. Wilson, Darius Armstrong-James, Adilia Warris   +5 more
doaj   +1 more source

Interleukin-4 during post-exercise recovery negatively correlates with the production of phagocyte-generated oxidants

Frontiers in Physiology, 2023
Exhaustive run induced a biphasic oxidative response of circulating phagocytes in 16 amateur sportsmen. The first phase involved an increment just after exercise of enhanced whole blood chemiluminescence normalized per phagocyte count, whereas in the ...
Adam Chmielecki, Krzysztof Bortnik, Szymon Galczynski, Karolina Kopacz, Gianluca Padula, Hanna Jerczynska, Robert Stawski, Dariusz Nowak   +7 more
doaj   +1 more source

PhagoStat a scalable and interpretable end to end framework for efficient quantification of cell phagocytosis in neurodegenerative disease studies [PDF]

, 2023
Quantifying the phagocytosis of dynamic, unstained cells is essential for evaluating neurodegenerative diseases. However, measuring rapid cell interactions and distinguishing cells from background make this task very challenging when processing time-lapse phase-contrast video microscopy.
arxiv   +1 more source

The physiology of foamy phagocytes in multiple sclerosis

Acta Neuropathologica Communications, 2018
Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by massive infiltration of immune cells, demyelination, and axonal loss.
Elien Grajchen, J. Hendriks, Jeroen F. J. Bogie   +2 more
semanticscholar   +1 more source

Phagocytes and demonstration of Phagocytic activity

, 2022
In Greek, “Phagein” is for “to eat” or “devour”, and “-cyte” suffix in biology denoting “cell”. Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria and dead or dying cells. They are essential for fighting infections and for subsequent immunity. One litre of human blood contains about six billion phagocytes.
openaire   +1 more source

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Microbiology Spectrum, 2023
Mycobacterium abscessus, an intracellular nontuberculous mycobacterium, is considered the most pathogenic species among the group of rapidly growing mycobacteria. The resistance of M. abscessus to the host innate response contributes to its pathogenicity
Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski   +5 more
doaj   +1 more source

Proinflammatory response of canine trophoblasts to Brucella canis infection [PDF]

, 2017
Brucella canis infection is an important cause of late-term abortion in pregnant bitches. The pathophysiological mechanisms leading to B. canis–induced abortion are unknown, but heavily infected trophoblasts are consistently observed.
Baldi, Pablo Cesar, Fernandez, Andrea Giselle, Ferrero, Mariana Cristina, Fossati, Carlos Alberto, Hielpos, María Soledad   +4 more
core   +1 more source

Immunometabolism of Phagocytes and Relationships to Cardiac Repair

Frontiers in Cardiovascular Medicine, 2019
Cardiovascular disease remains the leading cause of death worldwide. Myocardial ischemia is a major contributor to cardiovascular morbidity and mortality.
Shuang Zhang, Gael Bories, Connor W. Lantz, R. Emmons, Amanda C Becker, Esther Liu, M. Abecassis, L. Yvan-Charvet, E. Thorp   +8 more
semanticscholar   +1 more source

ENDOTHELIAL DYSFUNCTION AND “OXIDATIVE STRESS” BY THE NONNSTABLE COURSE OF ISCHEMIC HEART DISEASE

Медицинская иммунология, 2014
. The purpose of study was to compare phagocytic indexes, free oxygen radicals generation, activity of antioxidative protection, cytokine levels and von Willebrand factor (vWF) antigen in the patients with non–stable course of ischemic heart disease of ...
A. E. Kratnov, A. G. Borodin, A. A. Kratnov, E. S. Uglov, O. V. Shilova   +4 more
doaj   +1 more source