Results 61 to 70 of about 219,012 (412)
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis [PDF]
, 2016 TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative therapies for these diseases.
Barrios, Bibiana Elisabet +6 more
core +1 more source
Differential proteomics highlights macrophage-specific responses to amorphous silica nanoparticles [PDF]
Nanoscale, Royal Society of Chemistry, 2017, 9 (27), pp.9641 -
9658. 10.1039/c7nr02140b, 2018 The technological and economic benefits of engineered nanomaterials may be offset by their adverse effects on living organisms. One of the highly produced nanomaterials under such scrutiny is amorphous silica nanoparticles, which are known to have an appreciable, although reversible, inflammatory potential.
arxiv +1 more source
Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
Pathogens, 2020 Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death in immunocompromised individuals. The interactions of this yeast with host phagocytes are critical to disease outcome, and C. neoformans is equipped with an array of
Elizabeth A. Gaylord +2 more
doaj +1 more source
American Journal of Respiratory and Critical Care Medicine, 2016 RATIONALE The pulmonary mononuclear phagocyte system is a critical host defense mechanism composed of macrophages, monocytes, monocyte-derived cells, and dendritic cells.
A. N. Desch +24 more
semanticscholar +1 more source
The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of Yersinia pestis
Pathogens, 2020 Yersinia pestis, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must adapt to a wide range of host environments to achieve successful
Hana S. Fukuto +2 more
doaj +1 more source
Chemotactic Reaction Enhancement in One Dimension [PDF]
arXiv, 2021 Chemotaxis, the directional locomotion of cells towards a source of a chemical gradient, is an integral part of many biological processes - for example, bacteria motion, single-cell or multicellular organisms development, immune response, etc.
arxiv
Chemotactic predator-prey dynamics [PDF]
, 2010 A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown that steady hunting is unstable.
arxiv +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Química NovaThe aim of this study was to develop and characterize a Brazil nut oil microemulsion system and determine the effect of this microemulsion on the superoxide release in human phagocytes.
Karol Patel Fiori +8 more
doaj +1 more source
Neutrophil extracellular traps and their role in health and disease
South African Journal of Science, 2016 The human innate immune system is indispensable for protection against potentially invasive microbial and viral pathogens, either neutralising them or containing their spread until effective mobilisation of the slower, adaptive (specific), immune ...
Jan G. Nel +5 more
doaj +1 more source