Results 71 to 80 of about 86,040 (309)
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Biosynthesis of DNA for disease detection.
An aquatic plant breathes through pores in the atmosphere, creating a bacterial loop cycle. Harmful toxins and pathogens invade the foreign substrate and recessive genes.
Nur Aifiah Binti Ibrahim
doaj +1 more source
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen +7 more
wiley +1 more source
Targeting Frequent Efferocytosis in Tumor Microenvironment is a New Direction for Cancer Treatment
A variety of factors, such as dietary habits, the external environment, and individual genetic differences, can lead to the development of cancer. While chemotherapy and radiotherapy are commonly used for cancer treatment, drug resistance and side ...
Gangxing Zhu +9 more
doaj +1 more source
Phagocyte Escape of Leptospira: The Role of TLRs and NLRs
The spirochetal bacteria Leptospira spp. are causative agents of leptospirosis, a globally neglected and reemerging zoonotic disease. Infection with these pathogens may lead to an acute and potentially fatal disease but also to chronic asymptomatic renal
Ignacio Santecchia +8 more
doaj +1 more source
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan +10 more
wiley +1 more source
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang +4 more
wiley +1 more source
Targeting phagocytes: Learning from Staphylococcus aureus [PDF]
A particular group of white blood cells, better known as phagocytes, play a crucial role in the host defense against bacterial infections. However, Staphylococcus aureus is a major human bacterial pathogen that is able to secrete proteins that ...
Tromp, A.T.
core
Targeting mononuclear phagocytes for eradicating intracellular parasites [PDF]
Mononuclear phagocytes such as monocytes, tissue-specific macrophages and dendritic cells are primary actors in both innate and adaptive immunity, as well as tissue homoeostasis. They have key roles in a range of physiological and pathological processes,
Simon J. Foster +33 more
core +1 more source

