Phagocytic Clearance in Neurodegeneration [PDF]
The cellular and molecular mechanisms of phagocytic clearance of apoptotic cells and debris have been intensely studied in invertebrate model organisms and in the mammalian immune system. This evolutionarily conserved process serves multiple purposes.
Jennifer D. Sokolowski, James Mandell
openaire +3 more sources
A Turing mechanism in order to explain the patchy nature of Crohn's disease [PDF]
Crohn's disease is an inflammatory bowel disease (IBD) that is not well understood. In particular, unlike other IBDs, the inflamed parts of the intestine compromise deep layers of the tissue and are not continuous but separated and distributed through the whole gastrointestinal tract, displaying a patchy inflammatory pattern.
arxiv
False friends: Phagocytes as Trojan horses in microbial brain infections
Humans are constantly exposed to pathogenic microbes. The first line of cellular host defense is composed of “professional” phagocytes, cells that efficiently recognize pathogens, internalize them, and then marshal an array of antimicrobial mechanisms to
F. Santiago-Tirado, T. Doering
semanticscholar +1 more source
Interaction of surfactant and protein at the o/w interface and its effect on colloidal and biological properties of polymeric nanocarriers [PDF]
The use of polymer-based surfactants in the double-emulsion (water/oil/water, W/O/W) solvent-evaporation technique is becoming a widespread strategy for preparing biocompatible and biodegradable polymeric nanoparticles (NPs) loaded with biomolecules of interest in biomedicine, or biotechnology.
arxiv +1 more source
Phagocytes: A Holistic Defense and Protection Against Active P2P Worms [PDF]
Active Peer-to-Peer (P2P) worms present serious threats to the global Internet by exploiting popular P2P applications to perform rapid topological self-propagation. Active P2P worms pose more deadly threats than normal scanning worms because they do not exhibit easily detectable anomalies, thus many existing defenses are no longer effective.
arxiv
Therapeutic applications of phagocytes [PDF]
Les preparations de leucocytes, utilisees pour la therapie des infections mortelles, sont peu concentrees en monocytes, pas assez purifiees et de plus, sont couteuses. Les lignees cellulaires transformees gardent de nombreuses proprietes des phagocytes et pourraient remplacer les preparations de leucocytes.
P.L. Yap, H.A. Leaver
openaire +3 more sources
The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape [PDF]
Phagocytosis is the fundamental cellular process by which eukaryotic cells bind and engulf particles by their cell membrane. Particle engulfment involves particle recognition by cell-surface receptors, signaling and remodeling of the actin cytoskeleton to guide the membrane around the particle in a zipper-like fashion. Despite the signaling complexity,
arxiv
Scrambled Eggs: Apoptotic Cell Clearance by Non-Professional Phagocytes in the Drosophila Ovary
For half of a century, it has been known that non-professional phagocytes, such as fibroblasts, endothelial, and epithelial cells, are capable of efferocytosis (engulfment of apoptotic cells).
Sandy B Serizier, K. McCall
semanticscholar +1 more source
Chronic inflammation evoked by pathogenic stimulus during carcinogenesis
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
Phagocytes such as dendritic cells and macrophages, which are distributed in the small intestinal mucosa, play a crucial role in maintaining mucosal homeostasis by sampling the luminal gut microbiota.
Masatoshi Morikawa+6 more
semanticscholar +1 more source