Results 11 to 20 of about 273,745 (349)

PHAGOCYTOSIS

open access: bronzeMedicine, 1949
L. Joe Berry, Tom D. Spies
openalex   +3 more sources

Phagocytosis [PDF]

open access: yesCurrent Biology, 2011
SummaryPhagocytosis is defined as the receptor-mediated engulfment of large (≥0.5 μm) particles into plasma membrane-derived vacuoles called phagosomes. Following scission from the plasma membrane, the phagosomes undergo a maturation process, sequentially fusing with endosomes and lysosomes, ultimately becoming phagolysosomes — highly acidic and ...
Botelho, Roberto J., Grinstein, Sergio
openaire   +2 more sources

The roles of microglia and astrocytes in phagocytosis and myelination: Insights from the cuprizone model of multiple sclerosis

open access: yesGlia, 2022
In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between demyelination and remyelination can trigger progressive degenerative processes.
M. K. Sen   +3 more
semanticscholar   +1 more source

Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

open access: yesCell Reports, 2021
Summary: Blockade of the inhibitory checkpoint SIRPα-CD47 promotes phagocytosis of cancer cells by macrophages and is a promising avenue in anti-cancer therapy.
Zhenghai Tang   +6 more
doaj   +1 more source

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

open access: yesNature Communications, 2021
The role of microglia cells in Alzheimer’s disease (AD) is well recognized, however their molecular and functional diversity remain unclear. Here, we isolated amyloid plaque-containing (using labelling with methoxy-XO4, XO4+) and non-containing (XO4 ...
Alexandra Grubman   +27 more
semanticscholar   +1 more source

Regulators of phagocytosis as pharmacologic targets for stroke treatment

open access: yesFrontiers in Pharmacology, 2023
Stroke, including ischemic and hemorrhagic stroke, causes massive cell death in the brain, which is followed by secondary inflammatory injury initiated by disease-associated molecular patterns released from dead cells. Phagocytosis, a cellular process of
Jian Cheng   +6 more
doaj   +1 more source

Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2

open access: yesCell Death and Differentiation, 2021
During cancer therapy, phagocytic clearance of dead cells plays a vital role in immune homeostasis. The nonapoptotic form of cell death, ferroptosis, exhibits extraordinary potential in tumor treatment.
Xiang Luo   +12 more
semanticscholar   +1 more source

In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA)

open access: yesFrontiers in Immunology, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames   +11 more
doaj   +1 more source

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