Results 21 to 30 of about 217,834 (263)
Expression of the Alpha8 Integrin Chain Facilitates Phagocytosis by Renal Mesangial Cells
Background/Aims: Healing of mesangioproliferative glomerulonephritis involves degradation of excess extracellular matrix, resolution of hypercellularity by apoptosis and phagocytosis of apoptotic cells. Integrin receptors participate in the regulation of
Ines Marek +7 more
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Phagocytosis: Our Current Understanding of a Universal Biological Process
Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm in diameter, including microorganisms, foreign substances, and apoptotic cells.
Eileen Uribe-Querol, Carlos Rosales
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High-throughput quantification of early stages of phagocytosis
Phagocytosis—the engulfment of cells and foreign bodies—is an important cellular process in innate immunity, development, and disease. Quantification of various stages of phagocytosis, especially in a rapid screening fashion, is an invaluable tool for ...
Jeremy Changyu Yeo +3 more
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Background Traumatic injury to axons produces breakdown of axons and myelin at the site of the lesion and then further distal to this where Wallerian degeneration develops.
Reichert Fanny +4 more
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Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites. [PDF]
Antibodies targeting merozoites are important in protection from malaria. Therefore, merozoite surface proteins are attractive vaccine candidates. There is a need for robust functional assays to investigate mechanisms of acquired immunity and vaccine ...
Danika L Hill +6 more
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Research progress of astrocyte phagocytosis in Alzheimer′s disease [PDF]
Astrocytes are heavily activated in Alzheimer′s disease, engulfing damaged synapses, Aβ proteins, Tau proteins, apoptotic cells and other substrates. However, these substrates are difficult to degrade, accumulate as the disease progresses, and impair the
QIN Xiaoli, ZHAO Linna, FU Rong, GUO Yuying, XU Shixin
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Phagocytosis Assay of Microglia for Dead Neurons in Primary Rat Brain Cell Cultures
Clearance of dead brain tissue including the dead neurons through phagocytosis is an endogenous function of microglia in the brain, which is critical for inflammation resolution after ischemic stroke or head trauma.
Xiurong Zhao +3 more
doaj +1 more source
Background Hyperhomocysteinemia (HHcy) has been linked to development of Alzheimer’s disease (AD) neuropathologically characterized by the accumulation of amyloid β (Aβ).
Xianwei Wang +13 more
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