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Current Biology, 2011 SummaryPhagocytosis is defined as the receptor-mediated engulfment of large (≥0.5 μm) particles into plasma membrane-derived vacuoles called phagosomes. Following scission from the plasma membrane, the phagosomes undergo a maturation process, sequentially fusing with endosomes and lysosomes, ultimately becoming phagolysosomes — highly acidic and ...
Botelho, Roberto J., Grinstein, Sergio
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Phagocytosis in Teleosts. Implications of the New Cells Involved
Biology, 2015 Phagocytosis is the process by which cells engulf some solid particles to form internal vesicles known as phagosomes. Phagocytosis is in fact a specific form of endocytosis involving the vesicular interiorization of particles. Phagocytosis is essentially
María Ángeles Esteban +3 more
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Scientific Reports, 2021 Following bacterial infection, macrophages produce pro-inflammatory cytokines in response to bacterial cell components, including lipopolysaccharide (LPS) and lipopeptide, and simultaneously phagocytize and digest the invading bacteria.
Takayuki Ueno +2 more
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Journal of Neuroinflammation, 2012 Background Intact myelin, which normally surrounds axons, breaks down in Wallerian degeneration following axonal injury and during neurodegenerative diseases such as multiple sclerosis.
Hadas Smadar +4 more
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SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging
Molecular Therapy: Nucleic Acids, 2021 Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular ...
Yong Lan +5 more
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Frontiers in Cellular Neuroscience, 2014 The innate-immune function of phagocytosis of apoptotic cells, tissue-debris, pathogens and cancer cells is essential for homeostasis, tissue repair, fighting infection and combating malignancy.
Miri eGitik +5 more
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Frontiers in Immunology, 2021 Fc receptor (FcR) is an important opsonin receptor on the surface of immune cells, playing an important role in antibody-dependent cell-mediated immunity.
Yanbo Hao +8 more
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Phosphoinositides and phagocytosis [PDF]
The Journal of Cell Biology, 2001 Phosphoinositide 3 kinases (PI3Ks)**Abbreviation used in this paper: PI3K, phosphoinositide 3 kinase. are known as regulators of phagocytosis. Recent results demonstrate that class I and III PI3Ks act consecutively in phagosome formation and maturation, and that their respective products, phosphatidylinositol 3,4,5-trisphosphate (PI[3,4,5]P3) and ...
Gillooly, David J. +2 more
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Identification of Drosophila gene products required for phagocytosis of Candida albicans.
PLoS Biology, 2006 Phagocytosis is a highly conserved aspect of innate immunity. We used Drosophila melanogaster S2 cells as a model system to study the phagocytosis of Candida albicans, the major fungal pathogen of humans, by screening an RNAi library representing 7,216 ...
Shannon L Stroschein-Stevenson +3 more
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The Entamoeba histolytica, Arp2/3 Complex Is Recruited to Phagocytic Cups through an Atypical Kinase EhAK1. [PDF]
PLoS Pathogens, 2015 The parasite Entamoeba histolytica is the etiological agent of amoebiasis and phagocytosis plays a key role in virulence of this organism. Signaling pathways involved in activation of cytoskeletal dynamics required for phagocytosis remain to be ...
Mrigya Babuta +3 more
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