Results 41 to 50 of about 215,058 (261)

STUDIES ON PHAGOCYTOSIS. [PDF]

Journal of the American Medical Association, 1906
The studies of Leishman, of Wright and Douglas, of Neufeld and Rimpau, of McFarland and Engle, and of others, have opened up a new field of investigation for the elucidation of the problem of the mechanism of immunity. The experiments that have been reported thus far have dealt almost entirely with the opsonic powers of the blood serum against ...
openaire   +2 more sources

Neutrophilic Phagocytosis

Eurasian Journal of Medicine, 2019
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Ali Bayram, Özden Vural, Ebubekir Bakan
doaj  

Syk activation during FcγR-mediated phagocytosis involves Syk palmitoylation and desulfenylation

Life Science Alliance
Upon Fc gamma R–mediated phagocytosis, Syk is palmitoylated by DHHC5 and desulfenylated on nearby Cys residues, and both modifications are important for Syk phosphorylation and phagocytosis.
Maxime Jansen, Jean-Marc Strub, Laurent Chaloin, Peter Coopman, Bruno Beaumelle   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Lipoprotein(a), an Opsonin, Enhances the Phagocytosis of Nontypeable Haemophilus influenzae by Macrophages

Journal of Immunology Research, 2021
We recently showed that both nontypeable Haemophilus influenzae (NTHi) and its surface plasminogen- (Plg-) binding proteins interact with lipoprotein(a) (Lp(a)) in a lysine-dependent manner.
Zhi Liu, Yuxin Li, Yu Wang, Zhe Liu, Yan Su, Qiang Ma, Runlin Han   +6 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Reticulocalbin-1 facilitates microglial phagocytosis. [PDF]

PLoS ONE, 2015
Phagocytosis is critical to the clearance of apoptotic cells, cellular debris and deleterious metabolic products for tissue homeostasis. Phagocytosis ligands directly recognizing deleterious cargos are the key to defining the functional roles of ...
Ying Ding, Nora B Caberoy, Feiye Guo, Michelle E LeBlanc, Chenming Zhang, Weiwen Wang, Feng Wang, Rui Chen, Wei Li   +8 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Phagocytosis of Microorganisms

Clinical Infectious Diseases, 1982
For its survival, the host depends on an elaborate internal defense system to protect against persistent invasion by pathogenic microorganisms. This system is composed primarily of cellular and humoral components of the circulatory system and includes the "professional" phagocytes (polymorphonuclear leukocytes, monocytes, and tissue macrophages ...
openaire   +4 more sources

Galectin-3 (MAC-2) Controls Microglia Phenotype Whether Amoeboid and Phagocytic or Branched and Non-phagocytic by Regulating the Cytoskeleton

Frontiers in Cellular Neuroscience, 2019
Myelin surrounding central nervous system (CNS) axons breaks down in multiple sclerosis (MS) and following traumatic axonal injury. Myelin-debris so produced is harmful to repair since it impedes remyelination in MS and the regeneration of traumatized ...
Fanny Reichert, Shlomo Rotshenker
doaj   +1 more source