Results 201 to 210 of about 435,809 (335)

Development and characterization of chimeric antigen receptor macrophages for amyloid clearance. [PDF]

Front Immunol
Balachandran M, Foster JS, Hancock TJ, Martin EB, Jackson JW, Angell N, Wall JS.   +6 more
europepmc   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Engineering macrophages for effective and safe targeting of CD47 cancer cells in the tumor microenvironment. [PDF]

J Immunother Cancer
Andón FT, Rosales Sánchez A, Pensado-López A, García-Campelo R, Takimoto CH.   +4 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Macrophages bend long fibres with flexural rigidity lower than 3 mN·nm² to avoid frustrated phagocytosis. [PDF]

Part Fibre Toxicol
Broßell D, Meyer-Plath A, Gräb O, Heunisch E, Kämpf K, Haase A, Wiemann M.   +6 more
europepmc   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

Phagocytosis of <i>Mycobacterium fortuitum</i> by Caprine Alveolar Macrophages Is Associated with iNOS and Pro-Inflammatory Markers Expression. [PDF]

Int J Mol Sci
Blay-Benach M, Cuenca-Lara P, Repullés J, Cervera Z, Pérez de Val B.   +4 more
europepmc   +1 more source

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

, 2010
A-Gonzalez, Albert, Albert, Aujla, Benson, Bluestone, Coombes, Fadok, Fadok, Finnemann, Finnemann, Freire-de-Lima, Hall, Hanayama, Hanayama, Hanayama, Hoffmann, Hsu, Huang, Huynh, Hynes, Ivanov, Ivanov, Jang, Johann, Kleinclauss, Lacy-Hulbert, Liang, Lucas, Lucas, Majai, McCarty, Miyake, Mucida, Mukundan, Nagata, Nandrot, Nishihara, Rubartelli, Savill, Savill, Savill, Schambach, Siewert, Stuart, Sugimoto, Torchinsky, Travis, Urban, Voll, Wu   +50 more
core   +1 more source

Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis.

Cell Stem Cell, 2010
A. Sierra, J. Encinas, J. Deudero, J. H. Chancey, G. Enikolopov, Linda Overstreet-Wadiche, S. Tsirka, M. Maletić-Savatić   +7 more
semanticscholar   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source