Results 21 to 30 of about 373,406 (347)

Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide

open access: yesScientific Reports, 2021
Following bacterial infection, macrophages produce pro-inflammatory cytokines in response to bacterial cell components, including lipopolysaccharide (LPS) and lipopeptide, and simultaneously phagocytize and digest the invading bacteria.
Takayuki Ueno   +2 more
doaj   +1 more source

Phagocytosis [PDF]

open access: yesImmunity, 2005
Phagocytosis requires receptor-mediated recognition of particles, usually in the guise of infectious agents and apoptotic cells. Phagosomes fuse with lysosomes to generate phagolysosomes, which play a key role in enzymatic digestion of the internalized contents into component parts.
Lynda M. Stuart   +2 more
openaire   +3 more sources

Complement-receptor-3 and scavenger-receptor-AI/II mediated myelin phagocytosis in microglia and macrophages

open access: yesNeurobiology of Disease, 2003
Microglia and macrophages express the αM/β2 integrin complement-receptor-3 (CR3/MAC-1; CD11b/CD18) and scavenger-receptor-AI/II (SRAI/II). Both can mediate myelin phagocytosis.
Fanny Reichert, Shlomo Rotshenker
doaj   +1 more source

Phagocytosis in Teleosts. Implications of the New Cells Involved

open access: yesBiology, 2015
Phagocytosis is the process by which cells engulf some solid particles to form internal vesicles known as phagosomes. Phagocytosis is in fact a specific form of endocytosis involving the vesicular interiorization of particles. Phagocytosis is essentially
María Ángeles Esteban   +3 more
doaj   +1 more source

SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging

open access: yesMolecular Therapy: Nucleic Acids, 2021
Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular ...
Yong Lan   +5 more
doaj   +1 more source

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin

open access: yesJournal of Neuroinflammation, 2012
Background Intact myelin, which normally surrounds axons, breaks down in Wallerian degeneration following axonal injury and during neurodegenerative diseases such as multiple sclerosis.
Hadas Smadar   +4 more
doaj   +1 more source

Phagocytic receptors activate and immune inhibitory receptor SIRPalpha inhibits phagocytosis through paxillin and cofilin

open access: yesFrontiers in Cellular Neuroscience, 2014
The innate-immune function of phagocytosis of apoptotic cells, tissue-debris, pathogens and cancer cells is essential for homeostasis, tissue repair, fighting infection and combating malignancy.
Miri eGitik   +5 more
doaj   +1 more source

Studying Membrane Biogenesis with a Luciferase-Based Reporter Gene Assay [PDF]

open access: yes, 2008
To study the coordination of different lipid synthesis pathways during membrane biogenesis it is useful to work with an experimental system where membrane biogenesis occurs rapidly and in an inducible manner.
Nohturfft, A, Zhang, S
core   +2 more sources

Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. [PDF]

open access: yes, 2019
Glioblastomas (GBM) are highly infiltrated by myeloid-derived innate immune cells that contribute to the immunosuppressive nature of the brain tumor microenvironment (TME).
Gao, Peisong   +14 more
core   +2 more sources

Target shape dependence in a simple model of receptor-mediated endocytosis and phagocytosis [PDF]

open access: yes, 2016
Phagocytosis and receptor-mediated endocytosis are vitally important particle uptake mechanisms in many cell types, ranging from single-cell organisms to immune cells.
Endres, Robert G., Richards, David M.
core   +2 more sources

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