Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation
Frontiers in Immunology, 2020 Clearance of cellular debris is required to maintain the homeostasis of multicellular organisms. It is intrinsic to processes such as tissue growth and remodeling, regeneration and resolution of injury and inflammation.
Johan O. Westman +2 more
semanticscholar +1 more source
Identification of Drosophila gene products required for phagocytosis of Candida albicans.
PLoS Biology, 2006 Phagocytosis is a highly conserved aspect of innate immunity. We used Drosophila melanogaster S2 cells as a model system to study the phagocytosis of Candida albicans, the major fungal pathogen of humans, by screening an RNAi library representing 7,216 ...
Shannon L Stroschein-Stevenson +3 more
doaj +2 more sources
Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain. [PDF]
, 2000 Phagocytosis and intracellular killing by bovine polymorphonuclear leukocytes (PMN) are important host defence mechanisms against mastitis caused by Staphylococcus aureus. We compared the phagocytosis and overall killing of a non slime-producing (NSP) S.
Barrio, Belén +3 more
core +3 more sources
The Entamoeba histolytica, Arp2/3 Complex Is Recruited to Phagocytic Cups through an Atypical Kinase EhAK1. [PDF]
PLoS Pathogens, 2015 The parasite Entamoeba histolytica is the etiological agent of amoebiasis and phagocytosis plays a key role in virulence of this organism. Signaling pathways involved in activation of cytoskeletal dynamics required for phagocytosis remain to be ...
Mrigya Babuta +3 more
doaj +1 more source
Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]
, 2015 Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall +77 more
core +1 more source
CD22 blockade restores homeostatic microglial phagocytosis in aging brains
Nature, 2019 Microglia maintain homeostasis in the central nervous system through phagocytic clearance of protein aggregates and cellular debris. This function deteriorates during ageing and neurodegenerative disease, concomitant with cognitive decline.
J. Pluvinage +17 more
semanticscholar +1 more source
Hemocyte-Mediated Phagocytosis in Crustaceans
Frontiers in Immunology, 2020 Phagocytosis is an ancient, highly conserved process in all multicellular organisms, through which the host can protect itself against invading microorganisms and environmental particles, as well as remove self-apoptotic cells/cell debris to maintain ...
Shan Liu +4 more
semanticscholar +1 more source
Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy. [PDF]
, 2018 Microglia are well known to play a critical role in maintaining brain homeostasis. However, their role in epileptogenesis has yet to be determined.
Adamo, Matthew A +13 more
core +2 more sources
Nanoparticle elasticity regulates phagocytosis and cancer cell uptake
Science Advances, 2020 The deformation of soft nanocapsules during cell binding and endocytosis leads to a lower cellular uptake than the stiff ones. The ability of cells to sense external mechanical cues is essential for their adaptation to the surrounding microenvironment ...
Yue Hui +6 more
semanticscholar +1 more source
High-throughput quantification of early stages of phagocytosis
BioTechniques, 2013 Phagocytosis—the engulfment of cells and foreign bodies—is an important cellular process in innate immunity, development, and disease. Quantification of various stages of phagocytosis, especially in a rapid screening fashion, is an invaluable tool for ...
Jeremy Changyu Yeo +3 more
doaj +1 more source