Results 41 to 50 of about 273,745 (349)
Nature Communications, 2020 Tumour cell phagocytosis by antigen presenting cells (APCs) is critical to the generation of antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-phagocytosis molecule CD47.
Christina A. von Roemeling +17 more
semanticscholar +1 more source
Identification of Drosophila gene products required for phagocytosis of Candida albicans.
PLoS Biology, 2006 Phagocytosis is a highly conserved aspect of innate immunity. We used Drosophila melanogaster S2 cells as a model system to study the phagocytosis of Candida albicans, the major fungal pathogen of humans, by screening an RNAi library representing 7,216 ...
Shannon L Stroschein-Stevenson +3 more
doaj +2 more sources
The Entamoeba histolytica, Arp2/3 Complex Is Recruited to Phagocytic Cups through an Atypical Kinase EhAK1. [PDF]
PLoS Pathogens, 2015 The parasite Entamoeba histolytica is the etiological agent of amoebiasis and phagocytosis plays a key role in virulence of this organism. Signaling pathways involved in activation of cytoskeletal dynamics required for phagocytosis remain to be ...
Mrigya Babuta +3 more
doaj +1 more source
CD22 blockade restores homeostatic microglial phagocytosis in aging brains
Nature, 2019 Microglia maintain homeostasis in the central nervous system through phagocytic clearance of protein aggregates and cellular debris. This function deteriorates during ageing and neurodegenerative disease, concomitant with cognitive decline.
John V. Pluvinage +17 more
semanticscholar +1 more source
Hemocyte-Mediated Phagocytosis in Crustaceans
Frontiers in Immunology, 2020 Phagocytosis is an ancient, highly conserved process in all multicellular organisms, through which the host can protect itself against invading microorganisms and environmental particles, as well as remove self-apoptotic cells/cell debris to maintain ...
Shan Liu +4 more
semanticscholar +1 more source
High-throughput quantification of early stages of phagocytosis
BioTechniques, 2013 Phagocytosis—the engulfment of cells and foreign bodies—is an important cellular process in innate immunity, development, and disease. Quantification of various stages of phagocytosis, especially in a rapid screening fashion, is an invaluable tool for ...
Jeremy Changyu Yeo +3 more
doaj +1 more source
Expression of the Alpha8 Integrin Chain Facilitates Phagocytosis by Renal Mesangial Cells
Cellular Physiology and Biochemistry, 2018 Background/Aims: Healing of mesangioproliferative glomerulonephritis involves degradation of excess extracellular matrix, resolution of hypercellularity by apoptosis and phagocytosis of apoptotic cells. Integrin receptors participate in the regulation of
Ines Marek +7 more
doaj +1 more source
Journal of Neuroinflammation, 2011 Background Traumatic injury to axons produces breakdown of axons and myelin at the site of the lesion and then further distal to this where Wallerian degeneration develops.
Reichert Fanny +4 more
doaj +1 more source
Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites. [PDF]
PLoS ONE, 2012 Antibodies targeting merozoites are important in protection from malaria. Therefore, merozoite surface proteins are attractive vaccine candidates. There is a need for robust functional assays to investigate mechanisms of acquired immunity and vaccine ...
Danika L Hill +6 more
doaj +1 more source
LC3-associated phagocytosis at a glance
Journal of Cell Science, 2019 Classically, canonical autophagy has been considered a survival mechanism initiated in response to nutrient insufficiency. We now understand that autophagy functions in multiple scenarios where it is necessary to maintain homeostasis. Recent evidence has
Bradlee L. Heckmann, D. Green
semanticscholar +1 more source