Results 61 to 70 of about 273,745 (349)
Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses
Frontiers in Immunology, 2019 Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody–antigen immune ...
M. Tay, K. Wiehe, J. Pollara
semanticscholar +1 more source
Physical Constraints and Forces Involved in Phagocytosis
Frontiers in Immunology, 2020 Phagocytosis is a specialized process that enables cellular ingestion and clearance of microbes, dead cells and tissue debris that are too large for other endocytic routes. As such, it is an essential component of tissue homeostasis and the innate immune
Valentin Jaumouillé, Clare M. Waterman
semanticscholar +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD
Respiratory Research, 2021 Background Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline.
R. Singh +8 more
doaj +1 more source
Chimeric antigen receptors that trigger phagocytosis
bioRxiv, 2018 Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T cells to kill cancer. The success of CAR-T cell therapies highlights the promise of programmed immunity, and suggests that applying CAR strategies to other immune cell lineages ...
Meghan A. Morrissey +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun +5 more
wiley +1 more source
The involvement of MiR-1-clathrin pathway in the regulation of phagocytosis.
PLoS ONE, 2014 Phagocytosis, one of the most powerful immune responses, is a complicated process regulated by many factors. However the regulation of phagocytosis mediated by microRNAs has not been extensively investigated.
Cuilian Liu, Jiajia Wang, Xiaobo Zhang
doaj +1 more source
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Reticulocalbin-1 facilitates microglial phagocytosis. [PDF]
PLoS ONE, 2015 Phagocytosis is critical to the clearance of apoptotic cells, cellular debris and deleterious metabolic products for tissue homeostasis. Phagocytosis ligands directly recognizing deleterious cargos are the key to defining the functional roles of ...
Ying Ding +8 more
doaj +1 more source
CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis
Nature, 2016 Atherosclerosis is the disease process that underlies heart attack and stroke. Advanced lesions at risk of rupture are characterized by the pathological accumulation of diseased vascular cells and apoptotic cellular debris.
Y. Kojima +17 more
semanticscholar +1 more source