Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites. [PDF]
PLoS ONE, 2012 Antibodies targeting merozoites are important in protection from malaria. Therefore, merozoite surface proteins are attractive vaccine candidates. There is a need for robust functional assays to investigate mechanisms of acquired immunity and vaccine ...
Danika L Hill +6 more
doaj +1 more source
Rab14 regulates the maturation of macrophage phagosomes containing the fungal pathogen Candida albicans and the outcome of the host-pathogen interaction [PDF]
, 2015 Date of Acceptance: 02/02/2015 Copyright © 2015, American Society for Microbiology.
Bain, Judith M +4 more
core +6 more sources
High-throughput quantification of early stages of phagocytosis
BioTechniques, 2013 Phagocytosis—the engulfment of cells and foreign bodies—is an important cellular process in innate immunity, development, and disease. Quantification of various stages of phagocytosis, especially in a rapid screening fashion, is an invaluable tool for ...
Jeremy Changyu Yeo +3 more
doaj +1 more source
The Entamoeba histolytica, Arp2/3 Complex Is Recruited to Phagocytic Cups through an Atypical Kinase EhAK1. [PDF]
PLoS Pathogens, 2015 The parasite Entamoeba histolytica is the etiological agent of amoebiasis and phagocytosis plays a key role in virulence of this organism. Signaling pathways involved in activation of cytoskeletal dynamics required for phagocytosis remain to be ...
Mrigya Babuta +3 more
doaj +1 more source
Physical phase field model for phagocytosis [PDF]
arXiv, 2023 We propose and study a simple, physical model for phagocytosis, i.e. the active, actin-mediated uptake of micron-sized particles by biological cells. The cell is described by the phase field method and the driving mechanisms of uptake are actin ratcheting, modeled by a dynamic vector field, as well as cell-particle adhesion due to receptor-ligand ...
arxiv
An Intuitive Automated Modelling Interface for Systems Biology [PDF]
EPTCS 9, 2009, pp. 73-86, 2009 We introduce a natural language interface for building stochastic pi calculus models of biological systems. In this language, complex constructs describing biochemical events are built from basic primitives of association, dissociation and transformation.
arxiv +1 more source
Preterm infants have deficient monocyte and lymphocyte cytokine responses to Group B Streptococcus [PDF]
, 2011 Group B streptococcus GBS) is an important cause of early-and late-onset sepsis in the newborn. Preterm infants have markedly increased susceptibility and worse outcomes, but their immunological responses to GBS are poorly defined.
Burgner, D. +9 more
core +3 more sources
Macrophage‐Mediated Tumor Cell Phagocytosis: Opportunity for Nanomedicine Intervention
Advanced Functional Materials, 2020 Macrophages are one of the most abundant non‐malignant cells in the tumor microenvironment, playing critical roles in mediating tumor immunity. As important innate immune cells, macrophages possess the potential to engulf tumor cells and present tumor ...
Xuefei Zhou, Xiangrui Liu, Leaf Huang
semanticscholar +1 more source
Journal of Neuroinflammation, 2011 Background Traumatic injury to axons produces breakdown of axons and myelin at the site of the lesion and then further distal to this where Wallerian degeneration develops.
Reichert Fanny +4 more
doaj +1 more source
Theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces [PDF]
arXiv, 2022 Phagocytosis is the process of engulfment and internalization of comparatively large particles by the cell, that plays a central role in the functioning of our immune system. We study the process of phagocytosis by considering a simplified coarse grained model of a three-dimensional vesicle, having uniform adhesion interaction with a rigid particle, in
arxiv