Results 61 to 70 of about 396,432 (395)
LC3-associated phagocytosis at a glance
Journal of Cell Science, 2019 Classically, canonical autophagy has been considered a survival mechanism initiated in response to nutrient insufficiency. We now understand that autophagy functions in multiple scenarios where it is necessary to maintain homeostasis. Recent evidence has
Bradlee L. Heckmann, D. Green
semanticscholar +1 more source
Bigraphical models for protein and membrane interactions [PDF]
EPTCS 11, 2009, pp. 3-18, 2009 We present a bigraphical framework suited for modeling biological systems both at protein level and at membrane level. We characterize formally bigraphs corresponding to biologically meaningful systems, and bigraphic rewriting rules representing biologically admissible interactions.
arxiv +1 more source
Expression of the Alpha8 Integrin Chain Facilitates Phagocytosis by Renal Mesangial Cells
Cellular Physiology and Biochemistry, 2018 Background/Aims: Healing of mesangioproliferative glomerulonephritis involves degradation of excess extracellular matrix, resolution of hypercellularity by apoptosis and phagocytosis of apoptotic cells. Integrin receptors participate in the regulation of
Ines Marek +7 more
doaj +1 more source
Phase field model for phagocytosis dynamics [PDF]
arXiv, 2021 The basic process of the innate immune system when phagocyte (white blood cell) engulf or swallow a target particle (bacterium or dead cell), is called phagocytosis. We apply the phase field approach in the spirit of [1], that couples the order parameter $u$ with 3D polarization (orientation) vector field $\textbf{P}$ of the actin network of the ...
arxiv
Macrophage‐Mediated Tumor Cell Phagocytosis: Opportunity for Nanomedicine Intervention
Advanced Functional Materials, 2020 Macrophages are one of the most abundant non‐malignant cells in the tumor microenvironment, playing critical roles in mediating tumor immunity. As important innate immune cells, macrophages possess the potential to engulf tumor cells and present tumor ...
Xuefei Zhou, Xiangrui Liu, Leaf Huang
semanticscholar +1 more source
The involvement of MiR-1-clathrin pathway in the regulation of phagocytosis.
PLoS ONE, 2014 Phagocytosis, one of the most powerful immune responses, is a complicated process regulated by many factors. However the regulation of phagocytosis mediated by microRNAs has not been extensively investigated.
Cuilian Liu, Jiajia Wang, Xiaobo Zhang
doaj +1 more source
Hemocyte-Mediated Phagocytosis in Crustaceans
Frontiers in Immunology, 2020 Phagocytosis is an ancient, highly conserved process in all multicellular organisms, through which the host can protect itself against invading microorganisms and environmental particles, as well as remove self-apoptotic cells/cell debris to maintain ...
Shan Liu +4 more
semanticscholar +1 more source
Journal of Neuroinflammation, 2020 Background Tibolone is a synthetic steroid used in clinical practice for the treatment of climacteric symptoms and osteoporosis. Active metabolites of tibolone, generated in target tissues, have an affinity for estrogen and androgen receptors. Astrocytes
Andrea Crespo-Castrillo +2 more
doaj +1 more source
Reticulocalbin-1 facilitates microglial phagocytosis. [PDF]
PLoS ONE, 2015 Phagocytosis is critical to the clearance of apoptotic cells, cellular debris and deleterious metabolic products for tissue homeostasis. Phagocytosis ligands directly recognizing deleterious cargos are the key to defining the functional roles of ...
Ying Ding +8 more
doaj +1 more source
Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]
Mol Cell Proteomics 12, 11 (2013) 3108-22, 2013 The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls.
arxiv +1 more source