Results 131 to 140 of about 13,993 (208)

Mechanisms of autophagosome formation

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
The formation of autophagosomes is a pivotal step in autophagy, a lysosomal degradation system that plays a crucial role in maintaining cellular homeostasis.
Yuko FUJIOKA, Nobuo N. NODA
doaj   +1 more source

Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery [PDF]

, 2014
Braeckmans, Kevin, De Smedt, Stefaan, Klumperman, Judith, Oorschot, Viola, Remaut, Katrien   +4 more
core   +1 more source

Experimental determination and mathematical modeling of standard shapes of forming autophagosomes

Nature Communications
The formation of autophagosomes involves dynamic morphological changes of a phagophore from a flat membrane cisterna into a cup-shaped intermediate and a spherical autophagosome.
Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima   +4 more
doaj   +1 more source

The Human Autophagy Core Complexes. [PDF]

Annu Rev Biochem
Hurley JH.
europepmc   +1 more source

C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals

The Journal of Clinical Investigation
The identification of genes that confer either extension of life span or accelerate age-related decline was a step forward in understanding the mechanisms of aging and revealed that it is partially controlled by genetics and transcriptional programs ...
Anais Franco-Romero, Valeria Morbidoni, Giulia Milan, Roberta Sartori, Jesper Wulff, Vanina Romanello, Andrea Armani, Leonardo Salviati, Maria Conte, Stefano Salvioli, Claudio Franceschi, Viviana Buonomo, Casey O. Swoboda, Paolo Grumati, Luca Pannone, Simone Martinelli, Harold B.J. Jefferies, Ivan Dikic, Jennifer van der Laan, Filipe Cabreiro, Douglas P. Millay, Sharon A. Tooze, Eva Trevisson, Marco Sandri   +23 more
doaj   +1 more source

Atg2/TRAPPIII-Ypt1 axis: deciphering the phagophore-ERES connection. [PDF]

Autophagy
Gómez-Sánchez R, Fromme JC, Ungermann C, Reggiori F.   +3 more
europepmc   +1 more source

Piecemeal mitochondrial degradation in plants: a coordination between mitochondrial dynamics and mitophagosome formation. [PDF]

Autophagy
Ma J, Li C, Zhuang X.
europepmc   +1 more source

Mfi2: an outer mitochondrial membrane mitofissin required for mitophagy. [PDF]

Autophagy Rep
Furukawa K, Maruyama T, Sakai Y, Noda NN, Kanki T.   +4 more
europepmc   +1 more source

VPS34 in Autophagy, Cancer, and Cancer Therapy. [PDF]

Cells
Bartolini E, Janji B, Gao R.
europepmc   +1 more source

Selective degradation processes in plants are not limited to autophagy. [PDF]

Plant Cell Rep
Michalak KM, Bagniewska-Zadworna A.
europepmc   +1 more source