Results 111 to 120 of about 13,993 (208)
Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]
, 2018 Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel +2 more
core
Autophagy induction regulates influenza virus replication in a time-dependent manner [PDF]
, 2017 Autophagy plays a key role in host defence responses against microbial infections by promoting degradation of pathogens and participating in acquired immunity.
Abdoli, Asghar +12 more
core +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Integrative genomic and functional analyses reveal NINL as a modulator of tau aggregation
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Proteostasis dysfunction is a hallmark of frontotemporal dementia (FTD) and Alzheimer's disease (AD), yet the genetic and molecular pathways that disrupt protein homeostasis remain poorly understood. METHODS We integrated human genetics, transcriptomics, and functional studies to identify proteostasis network components involved ...
Samantha K. Swift +14 more
wiley +1 more source
LC3B Labeling on Terrestrial Isopod Adipocytes
Bio-Protocol, 2013 The LC3B protein plays a critical role in autophagy. Normally, this protein resides in the cytosol, but following cleavage and lipidation with phosphatidylethanolamine, LC3B associates with the phagophore.
Christine Braquart-Varnier +2 more
doaj +1 more source
The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases
Exploration, Volume 6, Issue 2, April 2026.This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li +3 more
wiley +1 more source
Cell biology: Receptors for selective recycling. [PDF]
, 2015 This is the author accepted manuscript. The final version is available from Nature at http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14532 ...
Rubinsztein, David C
core +1 more source
Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin [PDF]
, 2015 Autophagy is a lysosomal catabolic route for protein aggregates and damaged organelles which in different stress conditions, such as starvation, generally improves cell survival.
Catizone, Angiolina +8 more
core +2 more sources
Rab7b modulates autophagic flux by interacting with Atg4B [PDF]
, 2017 Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system.
Bakke, Oddmund +9 more
core +2 more sources
Autophagy in the fight against tuberculosis. [PDF]
, 2015 Tuberculosis (TB), a chronic infectious disease mainly caused by the tubercle bacillus Mycobacterium tuberculosis, is one of the world's deadliest diseases that has afflicted humanity since ancient times. Although the number of people falling ill with TB
Bento, Carla F +2 more
core +2 more sources