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Synthetic Ligands of Myeloid C‐Type Lectin Receptors

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley   +1 more source

RAB5c orchestrates LC3-associated phagocytosis to promote microbicidal function of macrophages. [PDF]

open access: yesSci Adv
Freitas-Filho EG   +14 more
europepmc   +1 more source

The lysosomal carrier SLC29A3 supports antibacterial signaling, and promotes autophagy by activating TRPML1 in murine dendritic cells. [PDF]

open access: yesProc Natl Acad Sci U S A
Netting DJ   +5 more
europepmc   +1 more source

A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity. [PDF]

open access: yesDis Model Mech
Muir CF   +15 more
europepmc   +1 more source

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