Results 221 to 230 of about 22,892 (257)
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Protoplasma, 1967
Lysosomes were first described as cell particles or granules. I am now inclined to call them vacuoles, even when they appear as compact bodies, in order to emphasize the essentially extracellular character of their contents. Together with the phagosomes, they form what is conveniently referred to as the vacuolarapparatus [1], an intracellular digestive
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Lysosomes were first described as cell particles or granules. I am now inclined to call them vacuoles, even when they appear as compact bodies, in order to emphasize the essentially extracellular character of their contents. Together with the phagosomes, they form what is conveniently referred to as the vacuolarapparatus [1], an intracellular digestive
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The phagosome proteome: insight into phagosome functions.
The Journal of cell biology, 2001Phagosomes are key organelles for the innate ability of macrophages to participate in tissue remodeling, clear apoptotic cells, and restrict the spread of intracellular pathogens. To understand the functions of phagosomes, we initiated the systematic identification of their proteins.
J, Garin +8 more
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A Role for the Phagosome in Cytokine Secretion
Science, 2005Membrane traffic in activated macrophages is required for two critical events in innate immunity: proinflammatory cytokine secretion and phagocytosis of pathogens. We found a joint trafficking pathway linking both actions, which may economize membrane transport and augment the immune response. Tumor necrosis factor α (TNFα) is trafficked from the Golgi
Murray, R. Z. +3 more
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Characterization of the Mycobacterium tubercolosis phagosome
Journal of the American College of Cardiology, 1996Mycobacterium tuberculosis parasitizes host macrophages and resides in a phagosome that does not fuse with lysosomes and that resists acidification. Compared with phagosomes containing inert particles, the M. tuberculosis phagosome exhibits maturational arrest: plasma membrane proteins and early endocytic markers persist and there is limited ...
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The Journal of Protozoology, 1985
ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation
2016Phagocytosis plays an essential role in the immune system for the defense against invading microorganisms and the clearing of apoptotic cells. After internalization, the newly formed phagosome is constantly remodeled by fusion with early endosomes, late endosomes, and lysosomes.
Härtlova A +3 more
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A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomes
Journal of Cell Biology, 2023James Vines +2 more
exaly
Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules
Journal of Cell Biology, 1997Hanry Yu +2 more
exaly
pH changes in pinosomes and phagosomes in the ameba, Chaos carolinensis.
Journal of Cell Biology, 1982Taylor D L
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