Results 91 to 100 of about 6,315,792 (319)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Validating Dose Uncertainty Estimates Produced by AUTODIRECT: An Automated Program to Evaluate Deformable Image Registration Accuracy. [PDF]

, 2017
Deformable image registration is a powerful tool for mapping information, such as radiation therapy dose calculations, from one computed tomography image to another. However, deformable image registration is susceptible to mapping errors.
Chen, Josephine, Kim, Hojin, Kirby, Neil, Phillips, Justin, Pukala, Jason, Yom, Sue S   +5 more
core   +3 more sources

Ray Theory-Based Transcranial Phase Correction for Intracranial Imaging: A Phantom Study

IEEE Access, 2019
Ultrasonic imaging provides a non-invasive way to diagnose brain disease. However, due to imaging degradation effects from the phase-aberration and reverberation, it is still challenging to achieve an accurate transcranial imaging.
Chen Jiang, Yunqing Li, Boyi Li, Chengcheng Liu, Feng Xu, Kailiang Xu, Dean Ta   +6 more
doaj   +1 more source

Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging

Journal of Biomedical Optics, 2015
. The emerging technique of rapid prototyping with three-dimensional (3-D) printers provides a simple yet revolutionary method for fabricating objects with arbitrary geometry.
P. Ghassemi, Jianting Wang, Jianting Wang, A. Melchiorri, J. Ramella-Roman, S. Mathews, J. Coburn, B. Sorg, Yu Chen, T. Pfefer   +9 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Learned Primal-dual Reconstruction

, 2018
We propose the Learned Primal-Dual algorithm for tomographic reconstruction. The algorithm accounts for a (possibly non-linear) forward operator in a deep neural network by unrolling a proximal primal-dual optimization method, but where the proximal ...
Adler, Jonas, Öktem, Ozan
core   +1 more source

Iterative CT reconstruction using shearlet-based regularization [PDF]

, 2012
In computerized tomography, it is important to reduce the image noise without increasing the acquisition dose. Extensive research has been done into total variation minimization for image denoising and sparse-view reconstruction. However, TV minimization
Goossens, Bart, Pizurica, Aleksandra, Staelens, Steven, Van Holen, Roel, Vandeghinste, Bert, Vandenberghe, Stefaan, Vanhove, Christian   +6 more
core   +1 more source

A Structured Cleaving Mesh for Bioheat Transfer Application

IEEE Open Journal of Engineering in Medicine and Biology, 2020
Goal: The thermoregulation mechanism is a complex system that executes vital processes in the human body. Various models have been proposed to simulate the thermoregulatory response of an adult human to environmental stimuli.
Rohan Amare, Amir A. Bahadori, Steven Eckels   +2 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source