Results 101 to 110 of about 62,132 (278)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Advancements in Retinal Tissue-Mimicking Optical Coherence Tomography Phantoms: Materials, Properties, and Applications

BioChem
Optical coherence tomography (OCT) phantoms are essential tools for calibrating imaging systems, validating diagnostic algorithms, and bridging technological advancements with clinical applications. This review explores the development and application of
Mukhit Kulmaganbetov
doaj   +1 more source

Investigation of PolyVinyl Chloride Plastisol Tissue-Mimicking Phantoms for MR- and Ultrasound-Elastography

Frontiers in Physics, 2020
Objective: Realistic tissue-mimicking phantoms are essential for the development, the investigation and the calibration of medical imaging techniques and protocols.
Simon Chatelin, Elodie Breton, Ajeethan Arulrajah, Ajeethan Arulrajah, Céline Giraudeau, Benoit Wach, Laurence Meylheuc, Laurence Meylheuc, Jonathan Vappou   +8 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Automatic evaluation of the image quality of a mammographic phantom

Computer Methods and Programs in Biomedicine, 2004
In this work a method has been developed to analyse the digital image quality of a mammographic phantom by means of automatic process techniques. The techniques used for the digital image treatment are standard techniques as the image thresholding to detect objects, the regional growing for pixels pooling and the morphological operator application to ...
Mayo Nogueira, Patricia, Ródenas Escribá, Francisco De Asís, Verdú Martín, Gumersindo Jesús, Villaescusa, J.I, Campayo, Juan Manuel   +4 more
openaire   +4 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Head phantoms for electroencephalography and transcranial electric stimulation: a skull material study

, 2018
Physical head phantoms allow assessing source reconstruction procedures in electroencephalography and electrical stimulation profiles during transcranial electric stimulation. Volume conduction in the head is strongly influenced by the skull representing
Fiedler, Patrique, Haueisen, Jens, Hunold, Alexander, Strohmeier, Daniel   +3 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Advancements in Microwave Bone Imaging: Tomographic Reconstruction of an Anthropomorphic Calcaneus Phantom Using a Specialized Imaging Prototype for Bone Health Applications

IEEE Access
The evaluation and characterization of microwave imaging (MWI) prototype along with the optimization of imaging algorithm is a precursor step before the clinical study to measure in vivo dielectric properties.
Alessia Cannata, Adnan Elahi, Martin O'Halloran, Marco Pasian, Simona Di Meo, Giulia Matrone, Bilal Amin   +6 more
doaj   +1 more source

Quantifying admissible undersampling for sparsity-exploiting iterative image reconstruction in X-ray CT

, 2012
Iterative image reconstruction (IIR) with sparsity-exploiting methods, such as total variation (TV) minimization, investigated in compressive sensing (CS) claim potentially large reductions in sampling requirements.
Jørgensen, Jakob H., Pan, Xiaochuan, Sidky, Emil Y.   +2 more
core   +1 more source