Results 31 to 40 of about 666,519 (246)
Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis. [PDF]
Adv Sci (Weinh)Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Zhu YN +6 more
europepmc +2 more sources
A Review on Pharmaceutical Cocrystals [PDF]
International Journal for Pharmaceutical Research Scholars, 2018 A. S. Athira +3 more
openalex +2 more sources
Frontiers in Chemistry, 2021 The pharmaceutical cocrystal of caffeine-citric acid (CAF-CA, Form II) has been studied to explore the presence of hydrogen bonding interactions and structure-reactivity-property relationship between the two constituents CAF and Citric acid.
Priya Verma +5 more
doaj +1 more source
Journal of the Brazilian Chemical Society, 2023 Ezetimibe has significant lipid-lowering activity but presents low aqueous solubility. Co-crystallization techniques can be used to overcome this limitation.
D. Ronik +5 more
semanticscholar +1 more source
Pharmaceutical Cocrystals: An Overview [PDF]
Indian Journal of Pharmaceutical Sciences, 2017 Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient are the major constraints during the development of new product. Various approaches have been used for enhancement of solubility of poorly aqueous soluble drugs, but success of these approaches depends on physical and chemical nature of molecules being developed.
S Kumar, A Nanda
openaire +1 more source
Competitive cocrystallization and its application in the separation of flavonoids
IUCrJ, 2021 Recently, cocrystallization has been widely employed to tailor physicochemical properties of drugs in the pharmaceutical field. In this study, cocrystallization was applied to separate natural compounds with similar structures.
Yanming Xia +5 more
doaj +1 more source
Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal
Pharmaceutics, 2020 The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field.
Ricardo Machado Cruz +7 more
doaj +1 more source
The Vortex-Slurry Implementation: A Cheap, Easy, and Ultrafast Mechanochemical Tool to Synthesize/Screen Pharmaceutical Salts and Cocrystals. [PDF]
ACS OmegaN de Souza P +6 more
europepmc +2 more sources
Cocrystal Prediction Using Machine Learning Models and Descriptors
Applied Sciences, 2021 Cocrystals are of much interest in industrial application as well as academic research, and screening of suitable coformers for active pharmaceutical ingredients is the most crucial and challenging step in cocrystal development.
Medard Edmund Mswahili +6 more
doaj +1 more source
Enhanced Dissolution of Naproxen by Combining Cocrystallization and Eutectic Formation
Pharmaceutics, 2021 Improving dissolution properties of active pharmaceutical ingredients (APIs) is a critical step in drug development with the increasing occurrence of sparingly soluble APIs.
Hakyeong Kim, Soeun Jang, Il Won Kim
doaj +1 more source