Results 21 to 30 of about 1,115 (165)
Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems
Pharmaceutics, 2023 Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and stability present a significant challenge during their processing into final dosage forms.
Maan Singh +8 more
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Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals
Molecules, 2023 Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including anticancer, anti-inflammatory, antiviral and antioxidant properties, which makes them extensively studied.
Jia Xu +6 more
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Crystals, 2016 Cocrystallization could improve most physicochemical properties of specific active pharmaceutical ingredients, which has great potential in pharmaceutical development.
Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang
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Pharmaceutical Cocrystals: An Overview [PDF]
Indian Journal of Pharmaceutical Sciences, 2017 Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient are the major constraints during the development of new product. Various approaches have been used for enhancement of solubility of poorly aqueous soluble drugs, but success of these approaches depends on physical and chemical nature of molecules being developed.
S Kumar, A Nanda
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Procedia Chemistry, 2014 AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna +1 more
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Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications [PDF]
Crystal Growth & Design, 2018 peer ...
Maryam Karimi-Jafari +3 more
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Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids
Pharmaceutics, 2021 The manufacturing of solid pharmaceutical dosage forms composed of cocrystals requires numerous processes during which there is risk of dissociation into parent molecules.
Ryoma Tanaka +5 more
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, 2022 In this study, we investigated the effects of polymers on the pharmaceutical cocrystal formation process. Ibuprofen (IBU) was selected as the active pharmaceutical ingredient (API), nicotinamide (NIC) and saccharin (SAC) as the cocrystal coformer (CCF ...
Yang Chen (9737) +2 more
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Pharmaceuticals, 2023 Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.
Aytug Kara +4 more
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Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals [PDF]
Pharmaceutics, 2021 Mechanochemistry is considered an alternative attractive greener approach to prepare diverse molecular compounds and has become an important synthetic tool in different fields (e.g., physics, chemistry, and material science) since is considered an ecofriendly procedure that can be carried out under solvent free conditions or in the presence of minimal ...
Mizraín Solares-Briones +8 more
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