Results 1 to 10 of about 4,408 (188)
Solution Cocrystallization: A Scalable Approach for Cocrystal Production
Crystals, 2021 With an increasing interest in cocrystals due to various advantages, demand for large-scale cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach that utilizes several single-component crystallization concepts as ...
Nitin Pawar +2 more
exaly +3 more sources
Flavonoid-Based Cocrystals: A Comprehensive Study on Their Synthesis, Characterization, Physicochemical Properties and Applications [PDF]
MoleculesFlavonoids are naturally occurring compounds with reported anticancer, antimicrobial, anti-inflammatory, cardio-protective and antioxidant effects. They are increasingly incorporated in functional foods designed to promote health, enhance well-being, and
Urszula Izabela Maciołek +4 more
doaj +2 more sources
Cocrystal Engineering of Conjugated Polymer Blends via External Electric Field for Enhanced Charge Transport [PDF]
Advanced ScienceCocrystal engineering that combines different components into cocrystals renders the newly formed materials with innovative and multifunctional properties. However, this strategy is rather limitedly explored in conjugated polymer blends.
Yanan Guo, Hao Zheng, Juan Peng
doaj +2 more sources
Application of cosolvency and cocrystallization approach to enhance acyclovir solubility [PDF]
BMC ChemistryAcyclovir (ACY) is a commonly used antiviral drug with limited aqueous solubility and poor permeability. It is administered via oral and intravenous routes.
Elham Azad Khiabani +2 more
doaj +2 more sources
Formulation Strategies to Enhance the Solubility of Poorly Water-Soluble Drugs and Phytochemicals: Current Advances and Challenges [PDF]
PharmaceuticsThe low water solubility of numerous drug candidates and phytochemicals continues to pose a significant challenge in pharmaceutical development, greatly limiting their bioavailability and therapeutic performance.
Shery Jacob, Hiral Shah, Anroop B. Nair
doaj +2 more sources
Antibiotics, 2021 Cocrystallization is a promising approach to alter physicochemical properties of active pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile.
Noor Ul Islam +6 more
doaj +1 more source
Pharmaceutics, 2023 The chemotherapeutic agent known as 5-fluorouracil (5-FU) is an artificial fluoropyrimidine antimetabolite that has been widely used for its antineoplastic properties. Cocrystals of 5-fluorouracil (5-FU) with five different Schiff bases (benzylidene-urea
Farhat Jubeen +6 more
doaj +1 more source
Urea as a Cocrystal Former—Study of 3 Urea Based Pharmaceutical Cocrystals
Pharmaceutics, 2021 Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc.
Fucheng Leng, Koen Robeyns, Tom Leyssens
doaj +1 more source
Pharmaceutics, 2022 The mechanochemical synthesis of cocrystals has been introduced as a promising approach of formulating poorly water-soluble active pharmaceutical ingredients (APIs).
Maryam Karimi-Jafari +4 more
doaj +1 more source
Molecules, 2022 Melt-cast explosive 2,4-dinitroanisole (DNAN) crystal and its cocrystals DNAN/1,3-dinitrobenzene (DNB) and DNAN/2-nitroaniline (NA) were used to identify the effects of cocrystallization on the crystal structure, non-covalent interactions, and melting ...
Defu Wang, Lei Yang, Weihua Zhu
doaj +1 more source