Pharmaceutical Cocrystals: New Solid Phase Modification Approaches for the Formulation of APIs
Pharmaceutics, 2018 Cocrystals can be used as an alternative approach based on crystal engineering to enhance specific physicochemical and biopharmaceutical properties of active pharmaceutical ingredients (APIs) when the approaches to salt or polymorph formation do not meet
Anna Karagianni +2 more
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Organic Photothermal Cocrystals: Rational Design, Controlled Synthesis, and Advanced Application
Advanced Science, 2023 Organic photothermal cocrystals, integrating the advantages of intrinsic organic cocrystals and the fascinating photothermal conversion ability, hold attracted considerable interest in both basic science and practical applications, involving ...
Li Ming-De, Ming-Peng Zhuo
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Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications
Acta Pharmaceutica Sinica B, 2021 Pharmaceutical cocrystals are multicomponent systems in which at least one component is an active pharmaceutical ingredient and the others are pharmaceutically acceptable ingredients.
Ting Cai
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Pharmaceutical Cocrystals in Drug-Delivery Technologies: Advances from Rational Design to Therapeutic Applications [PDF]
PharmaceuticsPharmaceutical cocrystals are a well-established class of solid-state forms that can modulate the solubility, dissolution, stability, and bioavailability of active pharmaceutical ingredients without altering their molecular identity. Although traditional
Marina Monserrat Marcos Valdez +3 more
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Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis [PDF]
Advanced ScienceCocrystals are solid crystals formed by the combination of multiple components through non‐covalent interactions (NCIs). Despite their diverse structures and tunable optoelectronic properties, they cannot meet the demand for multi‐functionalization of ...
Ya‐Nan Zhu +6 more
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Flavonoid-Based Cocrystals: A Comprehensive Study on Their Synthesis, Characterization, Physicochemical Properties and Applications [PDF]
MoleculesFlavonoids are naturally occurring compounds with reported anticancer, antimicrobial, anti-inflammatory, cardio-protective and antioxidant effects. They are increasingly incorporated in functional foods designed to promote health, enhance well-being, and
Urszula Izabela Maciołek +4 more
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Cocrystallization of Ezetimibe with Organic Acids: Stoichiometric Optimization for Improved Solubility and Bioavailability [PDF]
PharmaceuticsBackground/Objectives: Pharmaceutical cocrystallization offers a promising strategy to enhance drug properties while preserving molecular integrity.
Ravi Maharjan +7 more
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Research note: Dietary curcumin cocrystals enhance egg quality and lipid metabolism in laying hens [PDF]
Poultry ScienceThis study was conducted to evaluate the effects of dietary curcumin cocrystals on laying performance, egg quality, and lipid metabolism in laying hens.
Linglian Kong +4 more
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Solid State Characterization and Dissolution Enhancement of Nevirapine Cocrystals [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: Novel cocrystals of nevirapine (NP) were designed and prepared with salicylamide and 3-hydroxy benzoic acid (3-HBA). Methods: The cocrystals were prepared by solvent drop grinding method by adding few drops of acetone to enhance the solubility ...
Prabhakar Panzade +3 more
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Crystals, 2021 Nowadays, many commercial drugs have poor solubility and bioavailability. Cocrystals are formulated to modulate active pharmaceutical ingredients’ properties with improved solubility, dissolution, and bioavailability compared to their pristine individual
Jianbing Tan, Jianhao Liu, Liling Ran
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