Results 21 to 30 of about 7,051 (200)
Research note: Dietary curcumin cocrystals enhance egg quality and lipid metabolism in laying hens [PDF]
Poultry ScienceThis study was conducted to evaluate the effects of dietary curcumin cocrystals on laying performance, egg quality, and lipid metabolism in laying hens.
Linglian Kong +4 more
doaj +2 more sources
Solid State Characterization and Dissolution Enhancement of Nevirapine Cocrystals [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: Novel cocrystals of nevirapine (NP) were designed and prepared with salicylamide and 3-hydroxy benzoic acid (3-HBA). Methods: The cocrystals were prepared by solvent drop grinding method by adding few drops of acetone to enhance the solubility ...
Prabhakar Panzade +3 more
doaj +1 more source
Cocrystals of Fenamic Acids with Nicotinamide
Crystal Growth & Design, 2011 Cocrystal formation between nicotinamide and five fenamic acid derivative drugs (flufenamic acid, niflumic acid, tolfenamic acid, mefenamic acid and meclofenamic acid) was investigated using solution-based and solid-state preparation methods. It was anticipated that the well-known acid–aromatic nitrogen heterosynthon would provide a sufficient driving ...
Fabian, Laszlo +6 more
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Crystals, 2021 Nowadays, many commercial drugs have poor solubility and bioavailability. Cocrystals are formulated to modulate active pharmaceutical ingredients’ properties with improved solubility, dissolution, and bioavailability compared to their pristine individual
Jianbing Tan, Jianhao Liu, Liling Ran
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Synthesis and Characterization of Nano-Sized 4-Aminosalicylic Acid–Sulfamethazine Cocrystals
Pharmaceutics, 2021 Drug–drug cocrystals are formulated to produce combined medication, not just to modulate active pharmaceutical ingredient (API) properties. Nano-crystals adjust the pharmacokinetic properties and enhance the dissolution of APIs.
Ala’ Salem +8 more
doaj +1 more source
Organic Cocrystals: Recent Advances and Perspectives for Electronic and Magnetic Applications
Frontiers in Chemistry, 2021 Cocrystal engineering is an advanced supramolecular strategy that has attracted a lot of research interest. Many studies on cocrystals in various application fields have been reported, with a particular focus on the optoelectronics field.
Mengjia Jiang +6 more
doaj +1 more source
Urea as a Cocrystal Former—Study of 3 Urea Based Pharmaceutical Cocrystals [PDF]
Pharmaceutics, 2021 Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc. The pharmaceutical industry is particularly interested in those cocrystals comprising a GRAS former in connection with the target API.
Fucheng Leng, Koen Robeyns, Tom Leyssens
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Recent advances in improving oral drug bioavailability by cocrystals [PDF]
BioImpacts, 2018 Introduction: Oral drug delivery is the most favored route of drug administration. However, poor oral bioavailability is one of the leading reasons for insufficient clinical efficacy.
Shahram Emami +3 more
doaj +1 more source
Cocrystals of Praziquantel with Phenolic Acids: Discovery, Characterization, and Evaluation
Molecules, 2022 Solvent-assisted grinding (SAG) and solution slow evaporation (SSE) methods are generally used for the preparation of cocrystals. However, even by using the same solvent, active pharmaceutical ingredient (API), and cocrystal coformer (CCF), the ...
Shiying Yang +9 more
doaj +1 more source
Polymorphism in Carbamazepine Cocrystals [PDF]
Crystal Growth & Design, 2008 Cocrystals of carbamazepine with nicotinamide and saccharin are shown to be polymorphic. Two polymorphs of carbamazepine-nicotinamide (CBZ-NCT) cocrystals and two polymorphs of carbamazepine-saccharin (CBZ-SAC) cocrystals were grown from solution in the presence of polymer heteronuclei. The two CBZ-NCT polymorphs, CBZ-NCT I and a polymer nucleated (PN)
William W, Porter +2 more
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