Results 41 to 50 of about 4,408 (188)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Supramolecular hair dyes: a new application of cocrystallization [PDF]

CrystEngComm, 2016
The manuscript presents the first report of hair dyes of various colors formed by the cocrystallization reactions. Unlike the most popular oxidative hair dye (OHD) products, these dyes are NH3 free and do not require H2O2 as a color developer. The importance of these new hair dyes products is further enhanced by recent reports which indicate that some ...
Delori, Amit, Urquhart, Andrew J., Oswald, Iain D. H.   +2 more
openaire   +3 more sources

Cocrystallization of Binary Silver Clusters Into Supramolecular Assembly to Regulate Aggregation‐Induced Emission and Thermally Activated Delayed Fluorescence

Aggregate
Aggregation‐induced emission (AIE) and thermally activated delayed fluorescence (TADF) are two optoelectronic properties with great potential for applications.
Wei‐Yi Liang, Hai‐Ling Wang, Peng‐Xu Lu, Pei‐Yu Liao, Wei Deng, Jian‐Hua Jia, Ming‐Liang Tong   +6 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Cocrystallization of Etodolac: Prediction of Cocrystallization, Synthesis, Solid State Characterization And In Vitro Drug Release

Marmara Pharmaceutical Journal, 2016
Bu arastirma kapsaminda, etodolak ko-kristallerinin sentezi  ve farkli koformerlerin yapilarinin aydinlatilmasi ile Hansen  cozunurluk paratmetrelerinin tayini calisilmistir. Etodolak’in  cozunurlugunun arttirilmasi ve dissolusyon ozelliginin  iyilestirilmesi amaciyla hazirlanan etodolak ko-kristallerinin  farkli koformerleri izlenmistir.
Dipak D Gadade, Sanjay S Pekamwar, Swaroop R Lahoti, Santosh D Patni, Mahesh C Sarode   +4 more
openaire   +2 more sources

Cocrystallization approach: Dissolution rate enhancement of carbamazepine with various coformers and virtual screening tools [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Cocrystallization is a promising solid-state modification used to enhance the dissolution rate and solubility of poorly water-soluble drugs, such as carbamazepine.
Taofik Rusdiana, Fitrianti Darusman, Iyan Sopyan, Silvi S. Putri   +3 more
doaj   +1 more source

Next Generation Hosts for Protein Recognition, Assembly and More

Chemistry – A European Journal, EarlyView.
The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley   +1 more source

Electrospray technique for cocrystallization of phytomolecules

Journal of King Saud University - Science, 2018
Abstract Poor aqueous solubility of most of the phytomolecules has restricted their vital biological use. Cocrystal approach can be one of the remedies for the problem. The present work was carried out with an objective to screen the potential of electrospray technique towards cocrystallization of quercetin (QUE). QUE was cocrystallized with caffeine
Sharvil Patil, Khushbu Chaudhari, Ravindra Kamble   +2 more
openaire   +1 more source

Preparation, characterization and evaluation of aspirin: benzoic acid cocrystals with enhanced pharmaceutical properties

Future Journal of Pharmaceutical Sciences, 2020
Background The cocrystallization process in pharmaceuticals has gained widespread attention as a recent method of modifying physicochemical properties without altering the pharmacological characteristics of drugs.
Braham Dutt, Manjusha Choudhary, Vikas Budhwar   +2 more
doaj   +1 more source

The Role of Iron‐Hyponitrite Intermediates in Biology and Insights From Synthetic Model Complexes

Chemistry – A European Journal, EarlyView.
Despite the difference in active site architecture, NO reduction by different NOR enzymes is expected to be linked by a common intermediate: hyponitrite (N2O22−). However, experimentally, very little is known about the coordination chemistry of iron with hyponitrite and the expected Fe‐hyponitrite intermediates.
Michael O. Lengel, Nicolai Lehnert
wiley   +1 more source