Results 31 to 40 of about 4,408 (188)
Angewandte Chemie, EarlyView.Multiphotochromic switching is controlled by silicon valency in a diarylethene‐based molecular architecture. Lewis base coordination gates electronic communication between the photochromic units, thereby enabling selective access to distinct switching states.
Lennart Stoess +2 more
wiley +2 more sources
Nucleophilic Gallyl Anions Enable Ga─Au Bimetallic Ammonia Activation
Angewandte Chemie, EarlyView.Unlocking gallyl nucleophiles: Counterion control enables formation of an unsupported gallyl─gold complex. Gold coordination induces a polarity switch at gallium, enabling cooperative activation of NH3 and related N─H/O─H substrates under mild conditions.
Hellen Videa +3 more
wiley +2 more sources
Pharmaceutics, 2021 A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate forms
Hanan Fael +4 more
doaj +1 more source
Engineering Cocrystals of Poorly Water-Soluble Drugs to Enhance Dissolution in Aqueous Medium
Pharmaceutics, 2018 Biopharmaceutics Classification System (BCS) Class II and IV drugs suffer from poor aqueous solubility and hence low bioavailability. Most of these drugs are hydrophobic and cannot be developed into a pharmaceutical formulation due to their poor aqueous ...
Indumathi Sathisaran +1 more
doaj +1 more source
Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization" [PDF]
Advanced Pharmaceutical Bulletin, 2020 -
Shahram Emami, Ali Shayanfar
openaire +3 more sources
Preparation and Characterization of Highly Water Soluble Curcumin – Dextrose Cocrystal [PDF]
Journal of Pure and Applied Chemistry Research, 2018 Curcumin is a natural food colorant isolated from rhizomes of turmeric (Curcuma longa). Despite its many favorable properties, curcumin is practically insoluble in water and relatively unstable, thus limiting its application.
Katherine Kho +2 more
doaj +1 more source
Improving the solubility of dexlansoprazole by cocrystallization with isonicotinamide
European Journal of Pharmaceutical Sciences, 2016 Cocrystallization of an active pharmaceutical ingredient (API) with a cocrystal former (co-former) is widely used to tailor the physicochemical properties of parent APIs. For proton-pump inhibitors (PPIs), the isolation of cocrystals has not been widely investigated.
Jianhui Li +6 more
openaire +2 more sources
Frontiers in PharmacologyTo overcome the poor solubility, permeability, and bioavailability of the plant isoflavone daidzein (DAI), a novel salt of DAI with anhydrous piperazine (PIP) was obtained based on cocrystallization strategy.
Jiacheng Meng +4 more
doaj +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Cocrystallization is an emerging approach for improving physico-chemical characteristics of an active pharmaceutical ingredient (API) for instance dissolution rate, solubility, stability in addition to mechanical properties without affecting their ...
Ameera A Radhi +3 more
doaj +1 more source
Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals
Molecules, 2023 Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including ...
Jia Xu +6 more
doaj +1 more source