Results 21 to 30 of about 6,443 (221)
Molecules, 2022 Melt-cast explosive 2,4-dinitroanisole (DNAN) crystal and its cocrystals DNAN/1,3-dinitrobenzene (DNB) and DNAN/2-nitroaniline (NA) were used to identify the effects of cocrystallization on the crystal structure, non-covalent interactions, and melting ...
Defu Wang, Lei Yang, Weihua Zhu
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Virtual Screening, Structural Analysis, and Formation Thermodynamics of Carbamazepine Cocrystals
Pharmaceutics, 2023 In this study, the existing set of carbamazepine (CBZ) cocrystals was extended through the successful combination of the drug with the positional isomers of acetamidobenzoic acid.
Artem O. Surov +5 more
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, 2023 The current research leverages the structural features and property superiorities along with benefits in protecting cardiovascular system of gallic acid (GLC) and gentisic acid (HGA) to optimize in vitro/vivo peculiarities of cardiotonic drug milrinone ...
Su-Su Meng (13904450) +11 more
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Pharmaceutical Cocrystals—A Review
Proceedings, 2021 The design and synthesis of pharmaceutical cocrystals have received great interest in the recent years. Cocrystallization of drug substances offers a tremendous opportunity for the development of new drug products with superior physical and ...
Sheetal S. Buddhadev, Kevin C. Garala
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Multicomponent Solids of Niflumic and Mefenamic Acids Based on Acid-Pyridine Synthon
Frontiers in Chemistry, 2022 The present study discusses comparative structural features of fourteen multicomponent solids of two non-steroidal anti-inflammatory drugs, Niflumic and Mefenamic acids, with amine and pyridine-based coformers.
Vineet Kumar +5 more
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Achieving Balanced Energetics through Cocrystallization [PDF]
Angewandte Chemie, 2019 AbstractAchieving energetic materials with a balanced ratio of oxidant to fuel is a challenge that has been difficult to meet through molecular synthesis. The alternative approach, composite formulation, fails to achieve intimate association of the components to the detriment of performance.
Michael K. Bellas, Adam J. Matzger
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Crystals, 2023 Pyruvic acid is an organic compound used in various fields (e.g., the pharmaceutical, cosmetic, food, and chemical industries) and subject to constantly growing demand.
Camila Caro Garrido +4 more
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Matrix Assisted Cocrystallization as an example of continuous and scalable method of obtaining pharmaceutical cocrystals on an industrial scale [PDF]
Farmacja Polska, 2021 Cocrystals can be defined as crystalline solids composed of at least two compounds in a stoichiometric ratio which interact nonionically. While one of the components is an active pharmaceutical ingredient (API) the term ‘pharmaceutical cocrystal’ could ...
Anna Magdalena Gołkowska +3 more
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Recent Advances in Pharmaceutical Cocrystals: From Bench to Market
Frontiers in Pharmacology, 2021 The pharmacokinetics profile of active pharmaceutical ingredients (APIs) in the solid pharmaceutical dosage forms is largely dependent on the solid-state characteristics of the chemicals to understand the physicochemical properties by particle size, size
Ravi Kumar Bandaru +7 more
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Exploring the cocrystallization potential of urea and benzamide [PDF]
Journal of Molecular Modeling, 2016 The cocrystallization landscape of benzamide and urea interacting with aliphatic and aromatic carboxylic acids was studied both experimentally and theoretically. Ten new cocrystals of benzamide were synthesized using an oriented samples approach via a fast dropped evaporation technique.
Cysewski, Piotr +3 more
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