Results 21 to 30 of about 1,824 (206)
Pharmaceutical cocrystals model drug–receptor interactions [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2011 M. Tutughamiarso, E. Egert
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Crystals, 2021 Nowadays, many commercial drugs have poor solubility and bioavailability. Cocrystals are formulated to modulate active pharmaceutical ingredients’ properties with improved solubility, dissolution, and bioavailability compared to their pristine individual
Jianbing Tan, Jianhao Liu, Liling Ran
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Crystals, 2022 The most favored approach for drug administration is the oral route. Several anticancer drugs come under this category and mostly lack solubility and oral bioavailability, which are the most common causes of inadequate clinical efficiency. Enhancing oral
Divya Dhatri Kara, Mahalaxmi Rathnanand
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Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis. [PDF]
Adv Sci (Weinh)Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Zhu YN +6 more
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A Review on Pharmaceutical Cocrystals [PDF]
International Journal for Pharmaceutical Research Scholars, 2018 A. S. Athira +3 more
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Enhanced Dissolution of Naproxen by Combining Cocrystallization and Eutectic Formation
Pharmaceutics, 2021 Improving dissolution properties of active pharmaceutical ingredients (APIs) is a critical step in drug development with the increasing occurrence of sparingly soluble APIs.
Hakyeong Kim, Soeun Jang, Il Won Kim
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Pharmaceutical Cocrystals: An Overview [PDF]
Indian Journal of Pharmaceutical Sciences, 2017 Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient are the major constraints during the development of new product. Various approaches have been used for enhancement of solubility of poorly aqueous soluble drugs, but success of these approaches depends on physical and chemical nature of molecules being developed.
S Kumar, A Nanda
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Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications [PDF]
Crystal Growth & Design, 2018 peer ...
Maryam Karimi-Jafari +3 more
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Antibiotics, 2021 Cocrystallization is a promising approach to alter physicochemical properties of active pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile.
Noor Ul Islam +6 more
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Synthesis and Characterization of Nano-Sized 4-Aminosalicylic Acid–Sulfamethazine Cocrystals
Pharmaceutics, 2021 Drug–drug cocrystals are formulated to produce combined medication, not just to modulate active pharmaceutical ingredient (API) properties. Nano-crystals adjust the pharmacokinetic properties and enhance the dissolution of APIs.
Ala’ Salem +8 more
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