Results 11 to 20 of about 1,303 (119)
Recent advances in pharmaceutical cocrystals of theophylline [PDF]
Natural Products and BioprospectingCurrently, cocrystallization is a promising strategy for tailoring the physicochemical properties of active pharmaceutical ingredients. Theophylline, an alkaloid and the most primary metabolite of caffeine, is a readily available compound found in tea ...
Yanxiao Jia +7 more
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Flavonoid-Based Cocrystals: A Comprehensive Study on Their Synthesis, Characterization, Physicochemical Properties and Applications [PDF]
MoleculesFlavonoids are naturally occurring compounds with reported anticancer, antimicrobial, anti-inflammatory, cardio-protective and antioxidant effects. They are increasingly incorporated in functional foods designed to promote health, enhance well-being, and
Urszula Izabela Maciołek +4 more
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Crystals, 2023 X-ray powder diffraction is a vital analytical tool that is used in pharmaceutical science. It is increasingly used to establish the crystal structure of a new pharmaceutical substance, in particular, cocrystal or its polymorphic forms.
Vladimir Chernyshev
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Enhancing the Solubility of Indomethacin: A Breakthrough with Cocrystal Formation [PDF]
PharmaceuticalsBackground/objectives: Pharmaceutical cocrystals have emerged as a promising strategy to enhance the solubility and bioavailability of poorly water-soluble drugs.
Hugo Pardo +3 more
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Superior Dissolution Behavior and Bioavailability of Pharmaceutical Cocrystals and Recent Regulatory Issues [PDF]
ACS Medicinal Chemistry Letters, 2022 Jian-Rong Wang, Xuefeng Mei
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Cocrystallization of Ezetimibe with Organic Acids: Stoichiometric Optimization for Improved Solubility and Bioavailability [PDF]
PharmaceuticsBackground/Objectives: Pharmaceutical cocrystallization offers a promising strategy to enhance drug properties while preserving molecular integrity.
Ravi Maharjan +7 more
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Crystals, 2022 The most favored approach for drug administration is the oral route. Several anticancer drugs come under this category and mostly lack solubility and oral bioavailability, which are the most common causes of inadequate clinical efficiency. Enhancing oral
Divya Dhatri Kara, Mahalaxmi Rathnanand
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Pharmaceutical Cocrystals—A Review
Proceedings, 2021 The design and synthesis of pharmaceutical cocrystals have received great interest in the recent years. Cocrystallization of drug substances offers a tremendous opportunity for the development of new drug products with superior physical and ...
Sheetal S. Buddhadev, Kevin C. Garala
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Obtaining Cocrystals by Reaction Crystallization Method: Pharmaceutical Applications
Pharmaceutics, 2021 Cocrystals have gained attention in the pharmaceutical industry due to their ability to improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble drugs. Conceptually, cocrystals are multicomponent solids that contain
Isabela Fanelli Barreto Biscaia +3 more
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Enhanced Dissolution of Naproxen by Combining Cocrystallization and Eutectic Formation
Pharmaceutics, 2021 Improving dissolution properties of active pharmaceutical ingredients (APIs) is a critical step in drug development with the increasing occurrence of sparingly soluble APIs.
Hakyeong Kim, Soeun Jang, Il Won Kim
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