Results 11 to 20 of about 2,349 (173)
Procedia Chemistry, 2014 AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna +1 more
exaly +4 more sources
, 2016 The reliability of solvent drop grinding (SDG), also referred to as liquid assisted grinding, wet cogrinding, or mechanochemistry, to facilitate cocrystal formation is addressed with a series of model cocrystals and pharmaceutical cocrystals.
Michael J. Zaworotko (1298718) +3 more
core +18 more sources
Urea as a Cocrystal Former-Study of 3 Urea Based Pharmaceutical Cocrystals. [PDF]
Pharmaceutics, 2021 Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc. The pharmaceutical industry is particularly interested in those cocrystals comprising a GRAS former in connection with the target API.
Leng F, Robeyns K, Leyssens T.
europepmc +6 more sources
New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties [PDF]
Pharmaceutics, 2023 This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal.
Panpan Ma +17 more
doaj +2 more sources
Pharmaceutical cocrystal of antibiotic drugs: A comprehensive review
Heliyon, 2022 Pharmaceutical cocrystals, which contain at least one active pharmaceutical ingredient (API), are still an attention-grabbing field for researchers. Two or more discrete molecules unite together by non-covalent bonds, e.g., hydrogen, Van der Waals, and π⋯
Mais Bashimam, Hind El-Zein
doaj +3 more sources
Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals [PDF]
Pharmaceutics, 2020 Two, well defined binary crystals with 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide (HIMO) as coformer and thiobarbituric acid (TBA) as well barbituric acid (BA) as Active Pharmaceutical Ingredients (APIs) were obtained by cocrystallization (from methanol ...
Aneta Wróblewska +8 more
doaj +2 more sources
Obtaining Cocrystals by Reaction Crystallization Method: Pharmaceutical Applications
Pharmaceutics, 2021 Cocrystals have gained attention in the pharmaceutical industry due to their ability to improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble drugs. Conceptually, cocrystals are multicomponent solids that contain
Isabela Fanelli Barreto Biscaia +3 more
doaj +2 more sources
Flavonoid-Based Cocrystals: A Comprehensive Study on Their Synthesis, Characterization, Physicochemical Properties and Applications [PDF]
MoleculesFlavonoids are naturally occurring compounds with reported anticancer, antimicrobial, anti-inflammatory, cardio-protective and antioxidant effects. They are increasingly incorporated in functional foods designed to promote health, enhance well-being, and
Urszula Izabela Maciołek +4 more
doaj +2 more sources
Enhancing the Solubility of Indomethacin: A Breakthrough with Cocrystal Formation [PDF]
PharmaceuticalsBackground/objectives: Pharmaceutical cocrystals have emerged as a promising strategy to enhance the solubility and bioavailability of poorly water-soluble drugs.
Hugo Pardo +3 more
doaj +2 more sources
Crystals, 2023 X-ray powder diffraction is a vital analytical tool that is used in pharmaceutical science. It is increasingly used to establish the crystal structure of a new pharmaceutical substance, in particular, cocrystal or its polymorphic forms.
Vladimir V. Chernyshev
doaj +3 more sources