Results 101 to 110 of about 2,773,562 (359)

Oiling-out Crystallization of Beta-Alanine onSolid Surfaces Controlled by Solvent Exchange [PDF]

arXiv, 2020
Droplet formation in oiling-out crystallization has important implication for separation and purification of pharmaceutical active ingredients by using an antisolvent. In this work, we report the crystallization processes of oiling-out droplets on surfaces during solvent exchange.
arxiv  

Spectrophotometric Estimation of Flutamide in Pure and in Pharmaceutical Preparations

, 2012
Three simple, rapid, precise, sensitive, and accurate visible spectrophotometric methods (A, B, and C) are described for the estimation of flutamide in both pure and pharmaceutical preparations.
H. Deepakumari, H. Revanasiddappa
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Early Warning of COVID-19 Hotspots using Mobility of High Risk Users from Web Search Queries [PDF]

arXiv, 2020
COVID-19 has disrupted the global economy and well-being of people at an unprecedented scale and magnitude. To contain the disease, an effective early warning system that predicts the locations of outbreaks is of crucial importance. Studies have shown the effectiveness of using large-scale mobility data to monitor the impacts of non-pharmaceutical ...
arxiv  

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

La industria farmacéutica granadina durante el franquismo (19361975)

Ars Pharmaceutica
Resumen Objetivo: Estudiamos los laboratorios farmacêuticos que estuvieron en funcionamiento en la provincia de Granada durante el franquismo (1936-1975), tanto los creados con anterioridad a la guerra civil, como los establecidos durante este conflicto
Antonio Bueno González, Raúl Rodríguez Nozal   +1 more
doaj   +1 more source

Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications

Acta Pharmaceutica Sinica B, 2021
Minshan Guo, Xiaojie Sun, Jiahui Chen, Ting Cai   +3 more
semanticscholar   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

Safety and efficacy of recovery-promoting drugs for motor function after stroke: A systematic review of randomized controlled trials

Journal of Rehabilitation Medicine, 2019
Objective: To investigate the efficacy and safety of drug interventions to promote motor recovery post-stroke. Data sources: CENTRAL, CINAHL, Embase, MEDLINE, SCOPUS and Web of Science.
Nerida Firth, Ruth N. Barker, Kathryn S. Hayward, Julie Bernhardt, Michelle Bellingan, Ronny Gunnarsson   +5 more
doaj   +1 more source