Results 81 to 90 of about 99,751 (312)

Determination of methyl salicylate in pharmaceutical preparations [PDF]

open access: yes, 1964
A method based on gas-liquid chromatographic technique is described for the determination of methyl salicylate in pharmaceutical preparations. 10% carbowax 20M is used as a stationary phase to resolve mixtures containing amyl, ethyl and methyl ...
B Warren, S G E Stevens
core   +1 more source

Mechanism of action of quercetin in regulating cellular autophagy in multiple organs of Goto-Kakizaki rats through the PI3K/Akt/mTOR pathway

open access: yesFrontiers in Medicine
ObjectiveThis experimental study investigated the protective function of quercetin on the liver, spleen, and kidneys of Goto-Kakizaki (GK) rats and explores its mechanism of action on autophagy-related factors and pathways.Materials and methodsGK rats ...
Zhiqun Guo   +18 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Spectrofluorimetric determination of fluoroquinolones in pharmaceutical preparations [PDF]

open access: yes, 2009
Simple, rapid and highly sensitive spectrofluorimetric method is presented for the determination of four fluoroquinolone (FQ) drugs. ciprofloxacin, enoxacin, norfloxacin and moxifloxacin in pharmaceutical preparations.
Ulu, Sevgi
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

La industria farmacéutica granadina durante el franquismo (19361975)

open access: yesArs Pharmaceutica
Resumen Objetivo: Estudiamos los laboratorios farmacêuticos que estuvieron en funcionamiento en la provincia de Granada durante el franquismo (1936-1975), tanto los creados con anterioridad a la guerra civil, como los establecidos durante este conflicto
Antonio Bueno González   +1 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

The Determination of Benzene Hexachloride (Hexachlorocyclohexane) in Pharmaceutical Preparations [PDF]

open access: yes, 1949
Summary Methods are suggested for the determination of benzene hexachloride in certain pharmaceutical preparations. These are based on alkaline dehydrochlorination using monoethanolamine or alcoholic potassium hydroxide.
W H C Shaw
core   +1 more source

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