Results 81 to 90 of about 785,080 (295)

Mechanism of action of quercetin in regulating cellular autophagy in multiple organs of Goto-Kakizaki rats through the PI3K/Akt/mTOR pathway

Frontiers in Medicine
ObjectiveThis experimental study investigated the protective function of quercetin on the liver, spleen, and kidneys of Goto-Kakizaki (GK) rats and explores its mechanism of action on autophagy-related factors and pathways.Materials and methodsGK rats ...
Zhiqun Guo, Zhiqun Guo, Jingyu Zhang, Jingyu Zhang, Mianxin Li, Mianxin Li, Zengwei Xing, Zengwei Xing, Xi Li, Xi Li, Jiaqi Qing, Jiaqi Qing, Yuan Zhang, Yuan Zhang, Lemei Zhu, Lemei Zhu, Mingxu Qi, Xuemin Zou, Xuemin Zou   +18 more
doaj   +1 more source

Explaining Pharmaceutical R&D Growth Rates at the Industry Level: New Perspectives and Insights [PDF]

This paper uses aggregate data for the major pharmaceutical companies in the U.S. to study the rate of growth in pharmaceutical R&D intensity over the period from 1952 to 2001.
Santerre, Rexford, Vernon, John, Giaccotto, Carmelo   +2 more
core  

Pharmaceutical preparations, except biologicals : 1998 [PDF]

, 2000
Current industrial report.

core  

Spectrophotometric determination of dopaminergic drugs used for Parkinson's disease, cabergoline and ropinirole, in pharmaceutical preparations

, 2007
Simple and reproducible spectrophotometric methods have been developed for determination of dopaminergic drugs used for Parkinson's disease, cabergoline (CAB) and ropinirole hydrochloride (ROP), in pharmaceutical preparations.
Caglar, Sena, Onal, Armağan
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Functional characteristics of fresh antitumor immune interferer GDF-15 in multiple cancers

Scientific Reports
We designed our study with the aim of conducting a comprehensive analysis of the role that GDF-15 plays in pan-cancer. Multiple databases were used to obtain GDF-15 expression.
Min Fang, Ziyu Wang, Yuxin Zhou, Fengrui Yang, Zhu Wu, Jian Xiao   +5 more
doaj   +1 more source

Pharmaceutical preparations, except biologicals : 2002 [PDF]

, 2003
Current industrial report.

core  

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Corrections to “FastLeakyResNet-CIR: A Novel Deep Learning Framework for Breast Cancer Detection and Classification”

IEEE Access
Presents corrections to the paper, (Corrections to “FastLeakyResNet-CIR: A Novel Deep Learning Framework for Breast Cancer Detection and Classification”).
Ruiming Zeng, Boan Qu, Wei Liu, Jianghao Li, Hongshen Li, Pingping Bing, Shuangni Duan, Lemei Zhu   +7 more
doaj   +1 more source

Comparison of Rheological and Sedimentation Behavior of Commercially Available Suspending Vehicles for Oral Pharmaceutical Preparations

, 2018
A pharmaceutical suspension is a semi-liquid dosage form suitable for patients being unable to swallow solid medicines such as tablets and capsules. A vehicle used for the preparation of pharmaceutical oral suspensions preferably shows pseudo-plastic ...
Hinrichs, Wouter L J, Ten Seldam, Inge E J, Woerdenbag, Herman J, Woerdenbag, Herman J; id_orcid, van der Linden, Isabella J, Hinrichs, Wouter L J; id_orcid, Dijkers, Eli C F, Visser, J Carolina, Veenendaal, Reinier F H   +8 more
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