Results 71 to 80 of about 821,942 (298)

In situ rewiring TAMs as annihilators by “Spark-relay” nanoinitiator with flexible reactant ratio for amplifying solid tumor immunotherapy

Acta Pharmaceutica Sinica B
Tailoring tumor-associated macrophages (TAMs) into the tumoricidal phenotype represents a high-profile strategy for tumor immunotherapy. However, the existing TAMs repolarization strategies are restricted by hostile microenvironmental stress and ...
Xinping Luo, Yingmeng Jiang, Qing Zhang, Jie Yu, Chenxi Zhou, Zhanwei Zhou, Minjie Sun   +6 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Twentieth report / Expert Committee on Specifications for Pharmaceutical Preparations

, 1963
"This session of the Expert Committee on Specifications for Pharmaceutical Preparations was held in Geneva from 19 to 23 November 1962"14, 13 ...
World Health Organization, World Health Organization. Expert Committee on Specifications for Pharmaceutical Preparations   +1 more
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Pharmaceutical preparations, except biologicals : 2002 [PDF]

, 2003
Current industrial report.

core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Twenty-third report / Expert Committee on Specifications for Pharmaceutical Preparations

, 1969
"The WHO Expert Committee on Specifications for Pharmaceutical Preparations met in Geneva from 25 to 29 November 1969"WHO/PHARM/70.45613 ...
World Health Organization, World Health Organization. Expert Committee on Specifications for Pharmaceutical Preparations   +1 more
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Pharmaceutical preparations, except biologicals : 2000 [PDF]

, 2001
Current industrial report.

core  

A novel approach for denoising electrocardiogram signals to detect cardiovascular diseases using an efficient hybrid scheme

Frontiers in Cardiovascular Medicine
BackgroundElectrocardiogram (ECG) signals are inevitably contaminated with various kinds of noises during acquisition and transmission. The presence of noises may produce the inappropriate information on cardiac health, thereby preventing specialists ...
Pingping Bing, Wei Liu, Zhixing Zhai, Jianghao Li, Zhiqun Guo, Yanrui Xiang, Binsheng He, Lemei Zhu   +7 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

WHO Expert Committee on Specifications for Pharmaceutical Preparations : forty-first report

, 2007
"The WHO Expert Committee on Specifications for Pharmaceutical Preparations met in Geneva from 16 to 20 October 2006"--Introduction156 ...
WHO Expert Committee on Specifications for Pharmaceutical Preparations. Meeting (2006 : Geneva, Switzerland), World Health Organization   +1 more
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