Results 101 to 110 of about 212,580 (355)
FastLeakyResNet-CIR: A Novel Deep Learning Framework for Breast Cancer Detection and Classification
IEEE AccessBreast cancer is a type of disease that primarily affects the breast tissue, and it is crucial to achieve early diagnosis for successful treatment and recovery.
Ruiming Zeng +7 more
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Química Nova, 2009 A gas chromatographic method has been developed for the assay of fluvastatin sodium (FLU). FLU was silylated with N,O-bis(trimethylsilyl)trifluoroacetamide-1% trimethylchlorosilane at 90 ºC for 30 min and analysed in a DB-1 column by capillary gas ...
Serap Saglik Aslan +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Why Deprescribing Instead of Not Prescribing? [PDF]
Geriatrics, Gerontology and AgingPrescribing medications involves complex cognitive processes, and mistakes in prescription can cause serious adverse events. Deprescribing is one of the last opportunities to prevent patient harm from the use of drugs that should be avoided, especially ...
Welma Wildes Amorim +2 more
doaj +1 more source
Lactoferrin as a Component of Pharmaceutical Preparations: An Experimental Focus. [PDF]
Pharmaceuticals (Basel), 2023 Guzmán-Mejía F +3 more
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Evaluation of new formulations for neutralizing antimicrobial preservatives in pharmaceutical preparations. [PDF]
Heliyon, 2023 Katerji A, Trefi S, Bitar Y, Ibrahim A.
europepmc +1 more source
POTENTIAL IMPACT OF WTO TARIFFS ON CROSS-BORDER TRADE. InterTradeIreland, 2019 [PDF]
, 2019 The nature of the trade arrangements that will be in place following the exit of the UK from the EU is currently unknown and will be the subject of considerable negotiation over the coming years.
Author, No
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